ArticleEnvironmental health perspectives2011
Prenatal lead exposure and weight of 0- to 5-year-old children in Mexico city.
Article in Environmental health perspectives, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed, 87 citations in OpenAlex.
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- Association Between Lead Exposure and Anthropometric Indicators in School-aged Children: A Longitudinal Study.Biological trace element research · 2026Article
- Prenatal and early postnatal lead exposure and later adulthood BMI: The Saint Louis baby tooth - Later life health study.Environmental research · 2026Article
- Get the Lead Out: A Community-Driven Approach to Characterize Urban Soil Lead Levels near a Battery Smelter.Environmental science & technology · 2026Article
- Prenatal exposure to essential and toxic elements in relation to infant growth trajectories.Environmental health : a global access science source · 2026Article
- Article
- Dietary Intake Is Associated with Biomarkers of Lead, Arsenic, and Cadmium in a Cohort of Mexican Adolescents.The Journal of nutrition · 2025Article
- Current Understanding of Sex Differences in Metal-Induced Diseases.Current environmental health reports · 2025Review
- Factors influencing brain recovery from stroke via possible epigenetic changes.Future science OA · 2024Review
- Early Life Origins of Cardio-Metabolic Outcomes in Boston Birth Cohort: Review of Findings and Future directions.Precision nutrition · 2023Article
- Article
- Joint associations among prenatal metal mixtures and nutritional factors on birth weight z-score: Evidence from an urban U.S. population.Environmental research · 2022Article
- Differential fat accumulation in early adulthood according to adolescent-BMI and heavy metal exposure.New directions for child and adolescent development · 2022Article
- Trimester-specific phthalate exposures in pregnancy are associated with circulating metabolites in children.PloS one · 2022Article
- Health Risk Assessment of Exposure to 15 Essential and Toxic Elements in Spanish Women of Reproductive Age: A Case Study.International journal of environmental research and public health · 2021Article
- Association between cumulative childhood blood lead exposure and hepatic steatosis in young Mexican adults.Environmental research · 2021Article
- Prenatal and Early Childhood Exposure to Lead and Repeated Measures of Metabolic Syndrome Risk Indicators From Childhood to Preadolescence.Frontiers in pediatrics · 2021Article
- Hair Metal Levels and Childhood Weight Gain.Iranian journal of public health · 2020Article
- Estimating the causal effect of prenatal lead exposure on prepulse inhibition deficits in children and adolescents.Neurotoxicology · 2020Article
- Prenatal Lead Exposure, Type 2 Diabetes, and Cardiometabolic Risk Factors in Mexican Children at Age 10-18 Years.The Journal of clinical endocrinology and metabolism · 2020Article
Corrections and comments
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Authors and funding
10 authors at 7 institutions in 4 countries.
Funding
Abstract
backgroundCumulative prenatal lead exposure, as measured by maternal bone lead burden, has been associated with smaller weight of offspring at birth and 1 month of age, but no study has examined whether this effect persists into early childhood.
objectiveWe investigated the association of perinatal maternal bone lead, a biomarker of cumulative prenatal lead exposure, with children's attained weight over time from birth to 5 years of age.
methodsChildren were weighed at birth and at several intervals up until 60 months. Maternal tibia and patella lead were measured at 1 month postpartum using in vivo K-shell X-ray fluorescence. We used varying coefficient models with random effects to assess the association of maternal bone lead with weight trajectories of 522 boys and 477 girls born between 1994 and 2005 in Mexico City.
resultsAfter controlling for breast-feeding duration, maternal anthropometry, and sociodemographic characteristics, a 1-SD increase in maternal patella lead (micrograms per gram) was associated with a 130.9-g decrease in weight [95% confidence interval (CI), -227.4 to -34.4 g] among females and a 13.0-g nonsignificant increase in weight among males (95% CI, -73.7 to 99.9 g) at 5 years of age. These associations were similar after controlling for concurrent blood lead levels between birth and 5 years.
conclusionsMaternal bone lead was associated with lower weight over time among female but not male children up to 5 years of age. Given that the association was evident for patellar but not tibial lead levels, and was limited to females, results need to be confirmed in other studies.
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