Trial reportNutrition journal2011
Effect of fruit and vegetable concentrates on endothelial function in metabolic syndrome: a randomized controlled trial.
Trial report in Nutrition journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01224743 (Effect of Fruit and Vegetable Concentrates on Endothelial Function in Persons With Metabolic Syndrome), which is not on this map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Fruit and Vegetable Concentrates on Endothelial Function in Persons With Metabolic Syndrome: A Randomized, Controlled, Crossover Trial
Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Effects of walnuts on endothelial function in overweight adults with visceral obesity: a randomized, controlled, crossover trial.Journal of the American College of Nutrition · 2012Trial
- Association of nutrient patterns and metabolic syndrome and its components in adults living in Tehran, Iran.Journal of diabetes and metabolic disorders · 2020Article
- Impact of healthy diet and physical activity on metabolic health in men and women: Study Protocol Clinical Trial (SPIRIT Compliant).Medicine · 2020Article
- Population Health Impact and Cost-Effectiveness of Community-Supported Agriculture Among Low-Income US Adults: A Microsimulation Analysis.American journal of public health · 2020Article
- Fruit and Vegetable Concentrate Supplementation and Cardiovascular Health: A Systematic Review from a Public Health Perspective.Journal of clinical medicine · 2019Article
- Berry Fruit Consumption and Metabolic Syndrome.Antioxidants (Basel, Switzerland) · 2016Review
- Cocoa Flavanol Cardiovascular Effects Beyond Blood Pressure Reduction.Journal of clinical hypertension (Greenwich, Conn.) · 2016Review
- Dietary nutrient intake and metabolic syndrome risk in Chinese adults: a case-control study.Nutrition journal · 2013Article
- Diet Quality, Physical Activity, and Weight Changes and Their Association With 6-Year Risk of Metabolic Syndrome in Mexican Adults.American journal of lifestyle medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveDehydrated fruit and vegetable concentrates provide an accessible form of phytonutrient supplementation that may offer cardioprotective effects. This study assessed the effects of two blends of encapsulated juice powder concentrates (with and without added berry powders) on endothelial function in persons with metabolic syndrome, a risk factor for type 2 diabetes and cardiovascular disease.
methodsRandomized, double blind, placebo controlled crossover clinical trial with three treatment arms. 64 adults with metabolic syndrome were enrolled and received 8-week sequences of each blend of the concentrates and placebo. The primary outcome measure was change in endothelial function (assessed as flow-mediated dilatation of the brachial artery) 2 hr after consuming a 75 g glucose load, after 8-weeks of daily consumption (sustained) or 2 hr after consumption of a single dose (acute). Secondary outcome measures included plasma glucose, serum insulin, serum lipids, and body weight.
resultsNo significant between-group differences in endothelial function with daily treatment for 8 weeks were seen. No other significant treatment effects were discerned in glucose, insulin, lipids, and weight.
conclusionEncapsulated fruit and vegetable juice powder concentrates did not alter insulin or glucose measures in this sample of adults with metabolic syndrome.
trial registrationclinicaltrials.gov NCT01224743.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.