ArticleCanadian journal of public health = Revue canadienne de sante publique
Using centralized laboratory data to monitor trends in herpes simplex virus type 1 and 2 infection in British Columbia and the changing etiology of genital herpes.
Article in Canadian journal of public health = Revue canadienne de sante publique. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 8 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Epidemiology of herpes simplex virus type 1 and genital herpes in Australia and New Zealand: systematic review, meta-analyses and meta-regressions.Epidemiology and infection · 2023Pooled it
- Epidemiology of herpes simplex virus type 1 in Canada: systematic review, meta-analyses, and meta-regressions.Frontiers in public health · 2023Pooled it
- Epidemiology of herpes simplex virus type 2 in Latin America and the Caribbean: systematic review, meta-analyses and metaregressions.Sexually transmitted infections · 2021Pooled it
- Herpes simplex virus type 1 in Europe: systematic review, meta-analyses and meta-regressions.BMJ global health · 2020Pooled it
- The Epidemiology of Herpes Simplex Virus Type 1 in Asia: Systematic Review, Meta-analyses, and Meta-regressions.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Pooled it
- Herpes simplex virus type 1 epidemiology in the Middle East and North Africa: systematic review, meta-analyses, and meta-regressions.Scientific reports · 2019Pooled it
- Herpes simplex virus type 1 epidemiology in Latin America and the Caribbean: Systematic review and meta-analytics.PloS one · 2019Pooled it
- Neonatal Herpes Simplex Virus Type 1 Infection and Jewish Ritual Circumcision With Oral Suction: A Systematic Review.Journal of the Pediatric Infectious Diseases Society · 2015Pooled it
- Large, Stable, Contemporary Interspecies Recombination Events in Circulating Human Herpes Simplex Viruses.The Journal of infectious diseases · 2020Article
- Mixing It Up: New Insights Into Interspecies Recombination Between Herpes Simplex Virus Type 1 and 2.The Journal of infectious diseases · 2020Article
- Article
- Estimating seroprevalence of herpes simplex virus type 1 among different Middle East and North African male populations residing in Qatar.Journal of medical virology · 2018Article
- The herpevac trial for women: Sequence analysis of glycoproteins from viruses obtained from infected subjects.PloS one · 2017Article
- Inhibitors of nucleotidyltransferase superfamily enzymes suppress herpes simplex virus replication.Antimicrobial agents and chemotherapy · 2014Article
- What is new from the Canadian Paediatric Society Committee on Infectious Diseases and Immunization?The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2014Article
- HSV-1 strain McKrae is more neuroinvasive than HSV-1 KOS after corneal or vaginal inoculation in mice.Virus research · 2013Article
- A herpes simplex virus 2 glycoprotein D mutant generated by bacterial artificial chromosome mutagenesis is severely impaired for infecting neuronal cells and infects only Vero cells expressing exogenous HVEM.Journal of virology · 2012Article
- Antiviral potential of selected Indian medicinal (ayurvedic) plants against herpes simplex virus 1 and 2.North American journal of medical sciences · 2012Article
- Comparison of the host immune response to herpes simplex virus 1 (HSV-1) and HSV-2 at two different mucosal sites.Journal of virology · 2012Article
- Mucosal herpes immunity and immunopathology to ocular and genital herpes simplex virus infections.Clinical & developmental immunology · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesUnderstanding the regional epidemiology of genital Herpes Simplex Virus (HSV) infections is important for clinical and public health practice, due to the increasing availability of type-specific serologic testing in Canada and the contribution of genital HSV-2 infection to ongoing HIV transmission. We used centralized laboratory data to describe trends in viral identifications of genital HSV in BC and assess the utility of these data for ongoing population surveillance.
methodsRecords of viral identifications (1997-2005) were extracted from the Provincial Public Health Microbiology & Reference Laboratory database. Classification as genital or other site was based on documented specimen site. We conducted a descriptive analysis of trends over time, and calculated odds of HSV-1 infection among individuals with genital herpes.
resultsOf 48,183 viral identifications, 56.8% were genital, 10.0% were peri-oral and 9.1% cutaneous; site was unknown for 22.9%. Among genital identifications, HSV-1 infection was more likely in females, younger age groups, and later time periods. The proportion of genital herpes due to HSV-1 increased over time from 31.4% to 42.8% in BC.
conclusionsOur analysis of population-level laboratory data demonstrates that the proportion of genital herpes due to HSV-1 is increasing over time in BC, particularly among women and younger age groups; this has implications for clinical practice including the interpretation of type-specific serology. Provincial viral identification data are useful for monitoring the distribution of genital HSV-1 and HSV-2 infections over time. Improving clinical documentation of specimen site would improve the utility of these data.
Indexed as
Identifiers
21714324PMC6974205W2115522030What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.