SynthesisPloS one2011
Self-guided psychological treatment for depressive symptoms: a meta-analysis.
Synthesis in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04839822 (Efficacy of the Digital Self-help Programme Edupression.Com® Evaluated Within a Randomized Controlled Trial in Mild to Moderate Unipolar Depressive Patients), which is not on this map. Cited by 108 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of the Digital Self-help Programme Edupression.Com® Evaluated Within a Randomized Controlled Trial in Mild to Moderate Unipolar Depressive Patients
Who cites it
108 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Self-Guided Psychological Interventions for the Treatment and Prevention of Eating Disorders: A Meta-Analysis of Randomized Controlled Trials.European eating disorders review : the journal of the Eating Disorders Association · 2025Pooled it
- Effectiveness of Digital Behavioral Activation Interventions for Depression and Anxiety: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- The effects of self-management interventions on depressive symptoms in adults with chronic physical disease(s) experiencing depressive symptomatology: a systematic review and meta-analysis.BMC psychiatry · 2021Pooled it
- Low intensity technology-delivered cognitive behavioral therapy for obsessive-compulsive disorder: a meta-analysis.BMC psychiatry · 2021Pooled it
- Smartphone applications for depression: a systematic literature review and a survey of health care professionals' attitudes towards their use in clinical practice.European archives of psychiatry and clinical neuroscience · 2020Pooled it
- Rapid Review and Meta-Meta-Analysis of Self-Guided Interventions to Address Anxiety, Depression, and Stress During COVID-19 Social Distancing.Frontiers in psychology · 2020Pooled it
- Self-Guided Web-Based Interventions: Scoping Review on User Needs and the Potential of Embodied Conversational Agents to Address Them.Journal of medical Internet research · 2017Pooled it
- PSYCHOLOGICAL TREATMENT OF DEPRESSION IN COLLEGE STUDENTS: A METAANALYSIS.Depression and anxiety · 2016Pooled it
- Characterizing patient-oriented tools that could be packaged with guidelines to promote self-management and guideline adoption: a meta-review.Implementation science : IS · 2016Pooled it
- Examining the Acceptability and Effectiveness of a Self-Directed, Web-Based Resource for Stress and Coping in University: Randomized Controlled Trial.JMIR mental health · 2026Trial
- Comparison of the Working Alliance in Blended Cognitive Behavioral Therapy and Treatment as Usual for Depression in Europe: Secondary Data Analysis of the E-COMPARED Randomized Controlled Trial.Journal of medical Internet research · 2024Trial
- Do baseline participant characteristics impact the effectiveness of a mobile health intervention for depressive symptoms? A post-hoc subgroup analysis of the CONEMO trials.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2024Trial
- Online remote behavioural intervention for tics in 9- to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation.Health technology assessment (Winchester, England) · 2023Trial
- Age, Motivation, and Emotion Regulation Skills Predict Treatment Outcome in an Internet-Based Self-Help Intervention for COVID-19 Related Psychological Distress.Frontiers in public health · 2022Trial
- Making Internet-delivered cognitive behaviour therapy scalable for cancer survivors: a randomized non-inferiority trial of self-guided and technician-guided therapy.Journal of cancer survivorship : research and practice · 2020Trial
- Improving the Course of Depressive Symptoms After Inpatient Psychotherapy Using Adjunct Web-Based Self-Help: Follow-Up Results of a Randomized Controlled Trial.Journal of medical Internet research · 2019Trial
- The Effectiveness of an Internet Intervention Aimed at Reducing Alcohol Consumption in Adults.Deutsches Arzteblatt international · 2019Trial
- A cluster randomized controlled trial of an online psychoeducational intervention for people with a family history of depression.BMC psychiatry · 2019Trial
- Effects of a depression-focused internet intervention in slot machine gamblers: A randomized controlled trial.PloS one · 2018Trial
- Trial
48 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundA number of trials have examined the effects of self-guided psychological intervention, without any contact between the participants and a therapist or coach. The results and sizes of these trials have been mixed. This is the first quantitative meta-analysis, aimed at organizing and evaluating the literature, and estimating effect size.
methodWe conducted systematic literature searches in PubMed, PsycINFO and Embase up to January 2010, and identified additional studies through earlier meta-analyses, and the references of included studies. We identified seven randomized controlled trials that met our inclusion criteria, with a total of 1,362 respondents. The overall quality of the studies was high. A post-hoc power calculation showed that the studies had sufficient statistical power to detect an effect size of d = 0.19.
resultsThe overall mean effect size indicating the difference between self-guided psychological treatment and control groups at post-test was d = 0.28 (p<0.001), which corresponds to a NNT of 6.41. At 4 to 12 months follow-up the effect size was d = 0.23. There was no indication for significant publication bias.
conclusionsWe found evidence that self-guided psychological treatment has a small but significant effect on participants with increased levels of depressive symptomatology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.