ArticleNanoscale research letters2011
Porous silicon nanoparticles for cancer photothermotherapy.
Article in Nanoscale research letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 90 citations in OpenAlex.
- Wafer-Scale Deterministic Fabrication of Axis-Ratio-Engineered Silicon Nanoparticles for On-Resonance Electric-Magnetic Dipole Interference.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Recent Advances in Nanocarrier-Based Drug Delivery Systems for Lung Cancer.International journal of nanomedicine · 2026Review
- Molecular Dynamics Modeling of Pulsed Laser Fragmentation of Solid and Porous Si Nanoparticles in Liquid Media.International journal of molecular sciences · 2023Article
- Harvesting Light To Produce Heat: Photothermal Nanoparticles for Technological Applications and Biomedical Devices.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Review
- Hyperpolarized MRI with silicon micro and nanoparticles: Principles and applications.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2021Review
- Light-Responsive Inorganic Biomaterials for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Review
- Nanoparticles Produced via Laser Ablation of Porous Silicon and Silicon Nanowires for Optical Bioimaging.Sensors (Basel, Switzerland) · 2020Article
- Porous Si Microparticles Infiltrated with Magnetic Nanospheres.Nanomaterials (Basel, Switzerland) · 2020Article
- Transferrin-targeted porous silicon nanoparticles reduce glioblastoma cell migration across tight extracellular space.Scientific reports · 2020Article
- Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma.Journal of nanobiotechnology · 2019Article
- Cell Cytometry: Review and Perspective on Biotechnological Advances.Frontiers in bioengineering and biotechnology · 2019Review
- Scalable Synthesis of Biodegradable Black Mesoporous Silicon Nanoparticles for Highly Efficient Photothermal Therapy.ACS applied materials & interfaces · 2018Article
- Review
- Stealth Biocompatible Si-Based Nanoparticles for Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2017Article
- Remotely Triggered Nano-Theranostics For Cancer Applications.Nanotheranostics · 2017Article
- Heterogeneous reduction of carbon dioxide by hydride-terminated silicon nanocrystals.Nature communications · 2016Article
- Localized Surface Plasmon Resonance Biosensing: Current Challenges and Approaches.Sensors (Basel, Switzerland) · 2015Review
- Colloidal solutions of luminescent porous silicon clusters with different cluster sizes.Nanoscale research letters · 2014Article
- Porous silicon advances in drug delivery and immunotherapy.Current opinion in pharmacology · 2013Review
- Comparison of oxidized porous silicon with bare porous silicon as a photothermal agent for cancer cell destruction based on in vitro cell test results.Lasers in medical science · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The in vitro cell tests and in vivo animal tests were performed to investigate the feasibility of the photothermal therapy based on porous silicon (PSi) in combination with near-infrared (NIR) laser. According to the Annexin V- fluorescein isothiocyanate Apoptosis assay test results, the untreated cells and the cells exposed to NIR laser without PSi treatment had a cell viability of 95.6 and 91.3%, respectively. Likewise, the cells treated with PSi but not with NIR irradiation also had a cell viability of 74.4%. Combination of these two techniques, however, showed a cell viability of 6.7%. Also, the cell deaths were mostly due to necrosis but partly due to late apoptosis. The in vivo animal test results showed that the Murine colon carcinoma (CT-26) tumors were completely resorbed without nearly giving damage to surrounding healthy tissue within 5 days of PSi and NIR laser treatment. Tumors have not recurred at all in the PSi/NIR treatment groups thereafter. Both the in vitro cell test and in vivo animal test results suggest that thermotherapy based on PSi in combination with NIR laser irradiation is an efficient technique to selectively destroy cancer cells without damaging the surrounding healthy cells.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.