ArticleCell & bioscience2011
A proteomic study of TAR-RNA binding protein (TRBP)-associated factors.
Article in Cell & bioscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 23 citations in OpenAlex.
- A working model for condensate RNA-binding proteins as matchmakers for protein complex assembly.RNA (New York, N.Y.) · 2022Review
- PDM4, a Pentatricopeptide Repeat Protein, Affects Chloroplast Gene Expression and Chloroplast Development inFrontiers in plant science · 2020Article
- Expression of TARBP1 protein in human non-small-cell lung cancer and its prognostic significance.Oncology letters · 2018Article
- HIC1 controls cellular- and HIV-1- gene transcription via interactions with CTIP2 and HMGA1.Scientific reports · 2016Article
- Proteomic approaches to uncovering virus-host protein interactions during the progression of viral infection.Expert review of proteomics · 2016Review
- Linking RNA Dysfunction and Neurodegeneration in Amyotrophic Lateral Sclerosis.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2015Review
- Expression of protein TARBP1 in human hepatocellular carcinoma and its prognostic significance.International journal of clinical and experimental pathology · 2015Article
- The Impact of Mass Spectrometry-Based Proteomics on Fundamental Discoveries in Virology.Annual review of virology · 2014Article
- Stress-related alcohol consumption in heavy drinkers correlates with expression of miR-10a, miR-21, and components of the TAR-RNA-binding protein-associated complex.Alcoholism, clinical and experimental research · 2014Article
- Human RNAi pathway: crosstalk with organelles and cells.Functional & integrative genomics · 2014Review
- HMGA1 directly interacts with TAR to modulate basal and Tat-dependent HIV transcription.RNA biology · 2013Article
- Cellular RNA helicases and HIV-1: insights from genome-wide, proteomic, and molecular studies.Virus research · 2013Review
- Tombusvirus P19 RNA silencing suppressor (RSS) activity in mammalian cells correlates with charged amino acids that contribute to direct RNA-binding.Cell & bioscience · 2012Article
- MicroRNAs and HIV-1: complex interactions.The Journal of biological chemistry · 2012Review
- The multiple functions of TRBP, at the hub of cell responses to viruses, stress, and cancer.Microbiology and molecular biology reviews : MMBR · 2012Review
- Replication competent HIV-1 viruses that express intragenomic microRNA reveal discrete RNA-interference mechanisms that affect viral replication.Cell & bioscience · 2011Article
- MicroRNAs and human retroviruses.Biochimica et biophysica actaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundThe human TAR RNA-binding protein, TRBP, was first identified and cloned based on its high affinity binding to the small hairpin trans-activation responsive (TAR) RNA of HIV-1. TRBP has more recently been found to be a constituent of the RNA-induced silencing complex (RISC) serving as a Dicer co-factor in the processing of the ~70 nucleotide pre-microRNAs(miRNAs) to 21-25 nucleotide mature miRNAs.
findingsUsing co-immunoprecipitation and protein-identification by mass spectrometry, we characterized intracellular proteins that complex with TRBP. These interacting proteins include those that have been described to act in protein synthesis, RNA modifications and processing, DNA transcription, and cell proliferation.
conclusionsOur findings provide a proteome of factors that may cooperate with TRBP in activities such as miRNA processing and in RNA interference by the RISC complex.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.