Evidence map›Paper›PMID 21709745›Full record

ArticleSubstance abuse and rehabilitation2011

The prevalence and clinical significance of inhalant withdrawal symptoms among a national sample.

Brian E Perron, Joseph E Glass, Brian K Ahmedani, Michael G Vaughn, Daniel E Roberts, Li-Tzy Wu

Open access · goldAbstract read
In one paragraph

Article in Substance abuse and rehabilitation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Difluoroethane Inhalant Abuse, Skeletal Fluorosis, and Withdrawal.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2020
    Article
  2. Review
  3. Does DSM-5 nomenclature for inhalant use disorder improve upon DSM-IV?Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2015
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Brian E PerronUniversity of Michigan, Ann Arbor, MI, USA.
Joseph E Glass
Brian K Ahmedani
Michael G Vaughn
Daniel E Roberts
Li-Tzy Wu
University of Michigan–Ann Arbor · USDuke University · USHenry Ford Health System · USSaint Louis University · USWashington University in St. Louis · US

Funding

GWB MENTAL HEALTH SERVICE RESEARCH TRAININGT32MH019960 · NIMH · WASHINGTON UNIVERSITY · PI Leopoldo J Cabassa, Byron James Powell · 1995 to 2026
$11.1M
Transdisciplinary Training in Addictions ResearchT32DA015035 · NIDA · WASHINGTON UNIVERSITY · PI Leopoldo J Cabassa, Patricia A Cavazos-Rehg · 2002 to 2026
$5.3M
MDMA and Other Hallucinogen Use: Onset and Abuse/DependenceR01DA019623 · NIDA · DUKE UNIVERSITY · PI WU, LI-TZY · 2007 to 2013
$1.1M
Classification of Substance Use Severity and Treatment Outcomes: NIDA CTN StudiesR33DA027503 · NIDA · DUKE UNIVERSITY · PI WU, LI-TZY · 2010 to 2012
$1.1M
Epdemiology of Non-Medical Prescription Anagesic UseR01DA019901 · NIDA · DUKE UNIVERSITY · PI WU, LI-TZY · 2007 to 2009
$416k
Classification of Substance Use Severity and Treatment Outcomes: NIDA CTN StudiesR21DA027503 · NIDA · DUKE UNIVERSITY · PI WU, LI-TZY · 2009 to 2009
$302k
Symptoms and Structure of Inhalant Use DisordersR03DA027832 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PERRON, BRIAN E · 2009 to 2010
$154k
NIDA NIH HHS R01 DA019623NIDA NIH HHS R01 DA019901NIDA NIH HHS R03 DA027832NIDA NIH HHS R21 DA027503NIDA NIH HHS R33 DA027503NIDA NIH HHS T32 DA015035NIMH NIH HHS T32 MH019960
6 · The paper itself

Abstract

backgroundInhalants are among the most common and dangerous forms of substance use, but very little research on inhalant use disorders exist. Unlike other substances, the Diagnostic and Statistical Manual, 4th edition (DSM-IV) indicates that inhalants do not have an associated withdrawal syndrome among persons who meet criteria for inhalant dependence.

methodsUsing data from the National Epidemiologic Survey on Alcohol and Related Conditions, this study examines the prevalence of withdrawal symptoms among inhalant users. Prevalence of inhalant withdrawal symptoms for inhalants was also compared with the prevalence of cocaine withdrawal symptoms to help determine the presence of an inhalant withdrawal syndrome.

resultsApproximately 47.8% of persons who met criteria for inhalant dependence reported experiencing three or more inhalant-related withdrawal symptoms that were clinically significant. Among those with inhalant dependence, almost half of the withdrawal symptoms were as common as the corresponding withdrawal symptoms experienced by persons with cocaine dependence. Furthermore, the percentage of persons with inhalant dependence reporting clinically significant inhalant withdrawal symptoms was almost equal to the percentage of persons with cocaine dependence reporting clinically significant cocaine withdrawal symptoms.

conclusionsThese data provide evidence for an inhalant-related withdrawal syndrome among persons with inhalant dependence. Revisions to DSM-IV should consider including inhalant withdrawal as a diagnostic criterion for this disorder.

Identifiers

PMID21709745
PMCPMC3123390
OpenAlexW1982376577

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.