Evidence map›Paper›PMID 21709689›Full record

ReviewNature reviews. Genetics2011

New approaches to disease mapping in admixed populations.

Michael F Seldin, Bogdan Pasaniuc, Alkes L Price

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 4 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 4 syntheses or guidelines pooled it, 186 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Improved multi-ancestry fine-mapping identifiesmedRxiv : the preprint server for health sciences · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Strategies for the Genomic Analysis of Admixed Populations.Annual review of biomedical data science · 2023
    Review
  16. Article
  17. Admixture Mapping in African Americans Identifies New Risk Loci for HCV-Related Cirrhosis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
    Article
  18. Article
  19. Article
  20. Article

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Michael F SeldinDepartment of Biochemistry and Molecular Medicine, University of California Davis, Davis, California, USA. mfseldin@ucdavis.edu
Bogdan Pasaniuc
Alkes L Price
Broad Institute · USHarvard University · USUniversity of California, Davis · US

Funding

The Interplay of Sociodemographic and Genetic Factors in SLE Health DisparitiesP60AR053308 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KATZ, PATRICIA P · 2006 to 2016
$11.8M
Methods for Genome-wide Association Studies in Admixed PopulationsR01HG006399 · NHGRI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI PRICE, ALKES L · 2011 to 2024
$6.3M
Admixture Mapping Development and Testing in AA SLER01AR050267 · NIAMS · UNIVERSITY OF CALIFORNIA DAVIS · PI SELDIN, MICHAEL F. · 2005 to 2009
$2.4M
MA Admixture Mapping Development &Application to NIDDMR01DK071185 · NIDDK · UNIVERSITY OF CALIFORNIA DAVIS · PI SELDIN, MICHAEL F. · 2005 to 2008
$1.9M
Enabling Imputation and CNV Analysis in Genetic Studies of African AmericansRC1GM091332 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI WILSON, JAMES GRAHAM · 2009 to 2010
$974k
NHGRI NIH HHS R01 HG006399NIAMS NIH HHS P60 AR053308NIAMS NIH HHS R01 AR050267NIDDK NIH HHS R01 DK071185NIGMS NIH HHS RC1 GM091332
6 · The paper itself

Abstract

Admixed populations such as African Americans and Hispanic Americans are often medically underserved and bear a disproportionately high burden of disease. Owing to the diversity of their genomes, these populations have both advantages and disadvantages for genetic studies of complex phenotypes. Advances in statistical methodologies that can infer genetic contributions from ancestral populations may yield new insights into the aetiology of disease and may contribute to the applicability of genomic medicine to these admixed population groups.

Indexed as

BiomarkersBlack or African AmericanChromosome MappingComputational BiologyGenetics, PopulationGenome-Wide Association StudyGenotypeHispanic or LatinoHumansModels, GeneticOligonucleotide Array Sequence AnalysisPolymorphism, Single NucleotideBiomarkers

Identifiers

PMID21709689
PMCPMC3142784
OpenAlexW2036740103

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.