Evidence map›Paper›PMID 21707235›Full record

ArticleScandinavian journal of primary health care2011

The relationship between HbA1c level, symptoms and self-rated health in type 2 diabetic patients.

Anni B S Nielsen, Dorte Gannik, Volkert Siersma, Niels de Fine Olivarius

Abstract read
In one paragraph

Article in Scandinavian journal of primary health care, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Prevalence and burden of diabetes mellitus-related symptoms in patients with type 2 diabetes mellitus: A cross-sectional study.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Correlates of self-rated health in people with diabetic peripheral neuropathy: a longitudinal study.Diabetic medicine : a journal of the British Diabetic Association · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Diabetes, Prenatal Depression, and Self-Rated Health in Latina Mothers.Diabetes spectrum : a publication of the American Diabetes Association · 2018
    Article
  17. Article
  18. GPs asking patients to self-rate their health: a qualitative study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2015
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anni B S NielsenResearch Unit for General Practice and Section of General Practice, Institute of Public Health, University of Copenhagen, Øster Farimagsgade 5, Copenhagen K, Denmark. annibrit@sund.ku.dk
Dorte Gannik
Volkert Siersma
Niels de Fine Olivarius

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveImproving glycaemic control is generally supposed to reduce symptoms experienced by type 2 diabetic patients, but the relationships between glycated haemoglobin (HbA(1c)), diabetes-related symptoms, and self-rated health (SRH) are unclarified. This study explored the relationships between these aspects of diabetes control.

designA cross-sectional study one year after diagnosis of type 2 diabetes. SUBJECTS: A population-based sample of 606 type 2 diabetic patients, median age 65.6 years at diagnosis, regularly reviewed in primary care.

main outcome measuresThe relationships between HbA(1c), diabetes-related symptoms, and SRH.

resultsThe patients' median HbA(1c) was 7.8 (reference interval: 5.4-7.4 % at the time of the study). 270 (45.2%) reported diabetes-related symptoms within the past 14 days. SRH was associated with symptom score (γ = 0.30, p < 0.001) and HbA(1c) (γ = 0.17, p = 0.038) after correction for covariates. The relation between HbA(1c) and symptom score was explained by SRH together with other confounders, e.g. hypertension (γ = 0.02, p = 0.40). The relation between the symptom fatigue and SRH was not explained by symptom score and significantly modified the direct association between symptom score and SRH.

conclusionsSymptom relief may not occur even when HbA(1c) level is at its lowest average level in the natural history of diabetes, and symptoms and SRH are closely linked. Monitoring symptoms in the clinical encounter to extend information on disease severity, as measured e.g. by HbA(1c), may help general practitioners and patients to understand the possible impact of treatments and of disease manifestations in order to obtain optimum disease control.

Indexed as

Health StatusAdultAgedCross-Sectional StudiesDiabetes ComplicationsDiabetes Mellitus, Type 2FemaleGeneral PracticeGlycated HemoglobinHumansMaleMiddle AgedSelf ReportGlycated Hemoglobin

Identifiers

PMID21707235
PMCPMC3347958

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.