ArticleInfection2011
Differences in outpatient antibiotic prescription in Italy's Lombardy region.
Article in Infection, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Safety of azithromycin in pediatrics: a systematic review and meta-analysis.European journal of clinical pharmacology · 2020Pooled it
- Pooled it
- Article
- Estimating variations in the use of antibiotics in primary care: Insights from the Tuscany region, Italy.The International journal of health planning and management · 2022Article
- Disparity in socio-economic status explains the pattern of self-medication of antibiotics in India: understanding from game-theoretic perspective.Royal Society open science · 2022Article
- Antibiotic use and associated factors in adult outpatients from 2000 to 2019.Pharmacology research & perspectives · 2021Article
- Antibiotic use in children and youths with asthma: a population-based case-control study.ERJ open research · 2021Article
- Drug Utilization Pattern of Antibiotics: The Role of Age, Sex and Municipalities in Determining Variation.Risk management and healthcare policy · 2020Article
- Safety of azithromycin in paediatrics: a systematic review protocol.BMJ paediatrics open · 2019Article
- Outpatient Antibiotic Prescribing for Older Adults in the United States: 2011 to 2014.Journal of the American Geriatrics Society · 2018Article
- Prevalence of antibiotic prescription in southern Italian outpatients: real-world data analysis of socioeconomic and sociodemographic variables at a municipality level.ClinicoEconomics and outcomes research : CEOR · 2018Article
- Consumption of antibiotics by children in Greece: a cross-sectional study.International journal of pediatrics & adolescent medicine · 2017Article
- Prevalence and Predictors of Self-Medication with Antibiotics in Al Wazarat Health Center, Riyadh City, KSA.BioMed research international · 2016Article
- Changes in drug prescribing to Italian community-dwelling elderly people: the EPIFARM-Elderly Project 2000-2010.European journal of clinical pharmacology · 2014Article
- Geographical differences in the prevalence of chronic polypharmacy in older people: eleven years of the EPIFARM-Elderly Project.European journal of clinical pharmacology · 2013Article
- Trends in outpatient antibiotic use in Israel during the years 2000-2010: setting targets for an intervention.Infection · 2013Article
- Variation in antibiotic prescriptions: is area deprivation an explanation? Analysis of 1.2 million children in Germany.Infection · 2013Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe assessed the antibiotic patterns of use and geographical distribution of prevalence and consumption by age in 15 Local Health Units (LHUs) of Italy's Lombardy region.
methodsA retrospective analysis of reimbursement data for the community-dwelling population in 2005 was performed. Prescriptions reimbursed by the National Health System and consumption as defined daily doses (DDD) per 1,000 inhabitants per day (DID) were analyzed. A logistic regression was performed to evaluate the association between antibiotic drug prescription and age, gender, and LHU of residence of the population.
resultsDuring 2005, a total of 3,120,851 people (34% of the population) received at least one antibiotic drug prescription. The highest prescription prevalence was observed in the 0-17 and 80 or more years age ranges (41.6 and 41.9%, respectively). Large differences were found in the prevalence rates between different LHUs (ranging from 28.7% in Milan to 39.4% in Brescia) and in DID (ranging from 12.6 DID in Sondrio to 18.9 DID in Brescia). The age and residence of the population were the main determinants of drug exposure. In particular, patients aged <18 years (odds ratio [OR] = 1.73; 95% confidence interval [CI] 1.73, 1.74), aged 65 years or older (OR = 1.64; 95% CI 1.63, 1.65), and those that live in Brescia (OR = 1.66; 95% CI 1.65, 1.66) had a statistically significant higher risk of antibiotic drug exposure.
conclusionsThe observed intra-regional differences underline the need for a careful monitoring with the aim to reduce antibiotic resistance and improve the rational use of drugs.
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