Evidence map›Paper›PMID 21705221›Full record

ReviewTrends in cell biology2011

Fly meets yeast: checking the correct orientation of cell division.

Gislene Pereira, Yukiko M Yamashita

Abstract readReview
In one paragraph

Review in Trends in cell biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Tumor suppressor APC is an attenuator of spindle-pulling forces duringProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  11. Article
  12. Article
  13. Symmetry from Asymmetry or Asymmetry from Symmetry?Cold Spring Harbor symposia on quantitative biology · 2017
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. When fate follows age: unequal centrosomes in asymmetric cell division.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gislene PereiraDeutsches Krebsforschungszentrum (DKFZ)-Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH) Alliance, German Cancer Research Center, Molecular Biology of Centrosomes and Cilia, Im Neuenheimer Feld 581, 69120 Heidelberg, Germany. g.pereira@dkfz.de
Yukiko M Yamashita

Funding

Physiological regulation and function of asymmetric stem cell divisionR01GM086481 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YAMASHITA, YUKIKO · 2009 to 2013
$1.7M
NIGMS NIH HHS R01 GM086481NIGMS NIH HHS R01GM086481
6 · The paper itself

Abstract

Cell division is generally thought to be a process that produces an exact copy of the mother cell by precisely replicating its genomic DNA, doubling organelles, and segregating them into two cells. Many cell types from bacteria to human cells divide asymmetrically, however, to generate daughter cells with distinct characteristics. Such asymmetric divisions are fundamental to the lifespan of a cell, to embryonic development, and to stem cell homeostasis. Asymmetric division requires coordination of cellular asymmetry and the cell division machinery. Accumulating evidence suggests that the basic molecular mechanisms that govern this process are conserved from yeast to humans. In this review we highlight similarities in the mechanisms of asymmetric cell division in yeast and Drosophila male germline stem cells (GSCs) in the hope of extracting common themes underlying several systems.

Indexed as

Asymmetric Cell DivisionAnimalsCell Cycle CheckpointsCell Cycle ProteinsCell DifferentiationCell PolarityCentrosomeDrosophilaDrosophila ProteinsFungal ProteinsGerm CellsMaleSaccharomyces cerevisiaeSignal TransductionSpindle ApparatusStem CellsCell Cycle ProteinsDrosophila ProteinsFungal Proteins

Identifiers

PMID21705221
PMCPMC3164393

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.