ArticleNanomedicine : nanotechnology, biology, and medicine2012
In vivo cancer imaging by poly(ethylene glycol)-b-poly(ɛ-caprolactone) micelles containing a near-infrared probe.
Article in Nanomedicine : nanotechnology, biology, and medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Pirfenidone-Loaded Polymeric Micelles as an Effective Mechanotherapeutic to Potentiate Immunotherapy in Mouse Tumor Models.ACS nano · 2023Article
- Thioether-Based Polymeric Micelles with Fine-Tuned Oxidation Sensitivities for Chemotherapeutic Drug Delivery.Biomacromolecules · 2022Article
- Potential Role of Curcumin and Its Nanoformulations to Treat Various Types of Cancers.Biomolecules · 2021Review
- Bone Marrow Stromal Cells Alleviate Secondary Damage in the Substantia Nigra After Focal Cerebral Infarction in Rats.Frontiers in cellular neuroscience · 2019Article
- Deoxyschizandrin Loaded Liposomes on the Suppression Lipid Accumulation in 3T3-L1 Adipocytes.Molecules (Basel, Switzerland) · 2018Article
- Quantitative Assessment of Nanoparticle Biodistribution by Fluorescence Imaging, Revisited.ACS nano · 2018Article
- Administration of raloxifene hydrochloride nanosuspensions partially attenuates bone loss in ovariectomized mice.RSC advances · 2018Article
- Differences in Nanoparticle Uptake in Transplanted and Autochthonous Models of Pancreatic Cancer.Nano letters · 2018Article
- Intravenous Administration of Bone Marrow-Derived Mesenchymal Stem Cell, but not Adipose Tissue-Derived Stem Cell, Ameliorated the Neonatal Hypoxic-Ischemic Brain Injury by Changing Cerebral Inflammatory State in Rat.Frontiers in neurology · 2018Article
- Carboxyl of Poly(D,L-lactide-co-glycolide) Nanoparticles of Perfluorooctyl Bromide for Ultrasonic Imaging of Tumor.Contrast media & molecular imaging · 2018Article
- Effect of size and pegylation of liposomes and peptide-based synthetic lipoproteins on tumor targeting.Nanomedicine : nanotechnology, biology, and medicine · 2017Article
- Detection of intramyocardially injected DiR-labeled mesenchymal stem cells by optical and optoacoustic tomography.Photoacoustics · 2017Article
- Luminescent Difluoroboron β-Diketonate PLA-PEG Nanoparticle.Biomacromolecules · 2017Article
- A prodrug micellar carrier assembled from polymers with pendant farnesyl thiosalicylic acid moieties for improved delivery of paclitaxel.Acta biomaterialia · 2016Article
- Grapefruit-derived Nanovectors Delivering Therapeutic miR17 Through an Intranasal Route Inhibit Brain Tumor Progression.Molecular therapy : the journal of the American Society of Gene Therapy · 2016Article
- Preparation, characterization, in vivo pharmacokinetics, and biodistribution of polymeric micellar dimethoxycurcumin for tumor targeting.International journal of nanomedicine · 2015Article
- In vivo molecular imaging of colorectal cancer using quantum dots targeted to vascular endothelial growth factor receptor 2 and optical coherence tomography/laser-induced fluorescence dual-modality imaging.Journal of biomedical optics · 2015Article
- Quantum dots targeted to vascular endothelial growth factor receptor 2 as a contrast agent for the detection of colorectal cancer.Journal of biomedical optics · 2014Article
- Polymeric micelles for apoptosis-targeted optical imaging of cancer and intraoperative surgical guidance.PloS one · 2014Article
- Novel tumor-targeting, self-assembling peptide nanofiber as a carrier for effective curcumin delivery.International journal of nanomedicine · 2014Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Noninvasive near-infrared (NIR) fluorescence imaging is a promising technique for the intraoperative assessment of solid tumor removal. We incorporated a lipophilic NIR probe, 1,1'-dioctadecyltetramethyl indotricarbocyanine iodide (DiR), in poly(ethylene glycol)-b-poly(ɛ-caprolactone) (PEG-b-PCL) micelles, resulting in DiR solubilization in water, occupying nanoscopic PEG-b-PCL micelles. DiR in a self-quenched or nonquenched state showed different kinetics of release from PEG-b-PCL micelles in vitro; however, both obtained high tumor delineation (tumor-to-muscle ratio of 30-43 from collected organs). These results suggest that PEG-b-PCL micelles with DiR are a promising nanosized imaging agent that will provide a basis for enhanced surgical guidance via NIR visualization of tumors. FROM THE CLINICAL EDITOR: In this paper, noninvasive near-infrared fluorescence imaging coupled with specific lipophilic probes is discussed as a promising technique for intraoperative assessment of solid tumor removal, leading to optimized outcomes for in toto removal of tumors.
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Registered trials
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