Evidence map›Paper›PMID 21703582›Full record

ReviewPM & R : the journal of injury, function, and rehabilitation2011

Biological basis of exercise-based treatments for musculoskeletal conditions.

Fabrisia Ambrosio, Ayman Tarabishy, Fawzi Kadi, Elke H P Brown, Gwendolyn Sowa

Abstract readReview
In one paragraph

Review in PM & R : the journal of injury, function, and rehabilitation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Gene therapy for inherited muscle diseases: where genetics meets rehabilitation medicine.American journal of physical medicine & rehabilitation · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fabrisia AmbrosioDepartment of Physical Medicine and Rehabilitation, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA. ambrosiof@upmc.edu
Ayman Tarabishy
Fawzi Kadi
Elke H P Brown
Gwendolyn Sowa

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
Electrical stimulation reverses the effect of age on skeletal muscle regenerationK01AG039477 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AMBROSIO, FABRISIA · 2011 to 2013
$325k
NIA NIH HHS K01 AG039477NIA NIH HHS P30 AG024827
6 · The paper itself

Abstract

Exercise-based therapies are the cornerstone of rehabilitation programs. While the benefits of exercise on systemic and tissue function are generally accepted, mechanisms underlying these benefits are sometimes poorly understood. An improved understanding of the effects of mechanical loading on molecular and cellular processes has the potential to lead to more disease-specific and efficacious exercise-based therapies. The purpose of this paper is to review the current literature examining the role of mechanical signaling on muscle and cartilage biology.

Indexed as

BiomarkersExerciseExercise TherapyHumansMusculoskeletal DiseasesBiomarkers

Identifiers

PMID21703582
PMCPMC4868068

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.