Evidence map›Paper›PMID 21703580›Full record

ReviewPM & R : the journal of injury, function, and rehabilitation2011

Cognitive impairment in acquired brain injury: a predictor of rehabilitation outcomes and an opportunity for novel interventions.

Ellen Whyte, Elizabeth Skidmore, Howard Aizenstein, Joseph Ricker, Meryl Butters

Abstract readReview
In one paragraph

Review in PM & R : the journal of injury, function, and rehabilitation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. How can social cognition be improved in neurological patients? a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
  2. Pooled it
  3. Comparing the CO-OP ApproachBrain sciences · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Telerehabilitation in Acquired Brain Injury.Physical medicine and rehabilitation clinics of North America · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Burn Injuries and Their Impact on Cognitive-Communication Skills in the Inpatient Rehabilitation Setting.Journal of burn care & research : official publication of the American Burn Association
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ellen WhyteDepartment of Psychiatry, School of Medicine, WPIC-BT 764, 3811 O'Hara St, Pittsburgh PA 15213, USA.
Elizabeth Skidmore
Howard Aizenstein
Joseph Ricker
Meryl Butters

Funding

MULTICENTER CAREER DEVELOPMENT PROGRAM FOR PHYSICAL AND OCCUPATIONAL THERAPYK12HD055931 · NICHD · WASHINGTON UNIVERSITY · PI HAYES, MARCIE HARRIS · 2007 to 2021
$12.7M
Donepezil to promote functional recovery post-strokeR01HD055525 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WHYTE, ELLEN M · 2009 to 2013
$2.1M
Web-based stroke education for patients and familiesR44NS052948 · NINDS · FOX LEARNING SYSTEMS, INC. · PI FOX, DEBRA L · 2008 to 2009
$789k
NICHD NIH HHS K12 HD055931NICHD NIH HHS R01 HD055525NICHD NIH HHS R01 HD055525-01A2NINDS NIH HHS R44 NS052948NINDS NIH HHS R44 NS 052948-02A2
6 · The paper itself

Abstract

Cognitive impairment is a common sequela in acquired brain injury and one that predicts rehabilitation outcomes. There is emerging evidence that impairments in cognitive functions can be manipulated by both pharmacologic and nonpharmacologic interventions to improve rehabilitation outcomes. By using stroke as a model for acquired brain injury, we review the evidence that links cognitive impairment to poor rehabilitation outcomes and discuss possible mechanisms to explain this association. Furthermore, we examine nascent promising research that suggests that interventions that target cognitive impairments can lead to better rehabilitation outcomes.

Indexed as

Brain InjuriesCognition DisordersDisease ProgressionHumansIncidencePrevalenceStrokeUnited States

Identifiers

PMID21703580
PMCPMC4492523

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.