ArticlePhysiology & behavior2012
Pontine and thalamic influences on fluid rewards: I. Operant responding for sucrose and corn oil.
Article in Physiology & behavior, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Flavor preferences conditioned by nutritive and non-nutritive sweeteners in mice.Physiology & behavior · 2017Article
- Drug-motivated behavior in rats with lesions of the thalamic orosensory area.Behavioral neuroscience · 2016Article
- Alterations in sucrose sham-feeding intake as a function of diet-exposure in rats maintained on calorically dense diets.Appetite · 2015Article
- Gastric bypass in rats does not decrease appetitive behavior towards sweet or fatty fluids despite blunting preferential intake of sugar and fat.Physiology & behavior · 2015Article
- Article
- Bilateral lesions of the thalamic trigeminal orosensory area dissociate natural from drug reward in contrast paradigms.Behavioral neuroscience · 2012Article
- Pontine and thalamic influences on fluid rewards: III. Anticipatory contrast for sucrose and corn oil.Physiology & behavior · 2012Article
- Pontine and thalamic influences on fluid rewards: II. Sucrose and corn oil conditioned aversions.Physiology & behavior · 2012Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The reward strength of orosensory sucrose and corn oil was measured using fixed and progressive ratio operant schedules. Because the orosensory effects of the stimuli were of interest, Experiment 1 compared operant responses for sucrose in sham and real feeding rats. The results demonstrated that rats would work for sucrose solutions without the accompanying postingestive effects. Furthermore, the break points for high concentrations of sucrose (1.0 M or 2.0 M) were significantly higher in sham feeding rats than in real feeding controls. Experiment 2 investigated the role of the parabrachial nucleus (PBN) and of the thalamic orosensory area (TOA) in sucrose and corn oil reward. During free access, rats with PBN lesions (PBNx) licked significantly less sucrose solution than their controls, but both groups ingested a similar volume of corn oil emulsion. When an operant was imposed, these same PBNx rats failed to respond for sucrose and continued only modestly for corn oil. In contrast, the TOA lesioned rats (TOAx) showed no impairment in responding for sucrose or corn oil during either the free access or operant sessions. Furthermore, rats with TOA lesions demonstrated significantly higher break points for sucrose than did their controls. Together, the data imply that the PBN but not the TOA is critical for the perception of, or responding to the reward value of sucrose and corn oil.
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Registered trials
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