Evidence map›Paper›PMID 21703172›Full record

ArticleJournal of hepatology2012

Who pulls the trigger: JNK activation in liver lipotoxicity?

Samar H Ibrahim, Gregory J Gores

Abstract readEditorialComment
In one paragraph

Article in Journal of hepatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. MLK3 as a regulator of disease progression in Non-alcoholic steatohepatitis.Liver international : official journal of the International Association for the Study of the Liver · 2014
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Samar H Ibrahim
Gregory J Gores

Funding

MECHANISMS OF LIVER CELL INJURYR01DK041876 · NIDDK · MAYO CLINIC ROCHESTER · PI GORES, GREGORY J. · 1992 to 2019
$3.6M
MECHANISMS OF LIVER CELL INJURYR37DK041876 · NIDDK · MAYO CLINIC ROCHESTER · PI GORES, GREGORY J. · 2000 to 2009
$2.9M
INTRACELLULAR PH IN LIVER CELL INJURYR29DK041876 · NIDDK · MAYO CLINIC COLL OF MEDICINE, ROCHESTER · PI GORES, GREGORY J. · 1989 to 1992
–
NIDDK NIH HHS DK41876NIDDK NIH HHS R01 DK041876NIDDK NIH HHS R37 DK041876
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Animalscdc42 GTP-Binding ProteinFatty AcidsHepatocytesMAP Kinase Signaling SystemNeuropeptidesrac1 GTP-Binding Proteinrac GTP-Binding Proteinscdc42 GTP-Binding ProteinFatty AcidsNeuropeptidesrac1 GTP-Binding ProteinRac1 protein, mouserac GTP-Binding Proteins

Identifiers

PMID21703172
PMCPMC3297468

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.