ArticleMagnetic resonance in medicine2012
Human brain iron mapping using atlas-based T2 relaxometry.
Article in Magnetic resonance in medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 59 citations in OpenAlex.
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- Multiparametric CEST and Z-spectrum analysis proton (ZAP) as biomarkers of human brain aging.Scientific reports · 2026Article
- TImaging neuroscience (Cambridge, Mass.) · 2025Article
- Perturbed iron biology in the prefrontal cortex of people with schizophrenia.Molecular psychiatry · 2023Article
- Model-based multi-parameter mapping.Medical image analysis · 2021Article
- Computing and visualising intra-voxel orientation-specific relaxation-diffusion features in the human brain.Human brain mapping · 2021Article
- Retention of Gadolinium in Brain Parenchyma: Pathways for Speciation, Access, and Distribution. A Critical Review.Journal of magnetic resonance imaging : JMRI · 2020Review
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- Magnetic resonance fingerprinting with quadratic RF phase for measurement of TMagnetic resonance in medicine · 2019Article
- Fast 3D magnetic resonance fingerprinting for a whole-brain coverage.Magnetic resonance in medicine · 2018Article
- Serial quantitative neuroimaging of iron in the intracerebral hemorrhage pig model.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2018Article
- Slice profile and BMagnetic resonance in medicine · 2017Article
- Music-based magnetic resonance fingerprinting to improve patient comfort during MRI examinations.Magnetic resonance in medicine · 2016Article
- Simultaneous TTomography (Ann Arbor, Mich.) · 2015Article
- Lateral ventricular cerebrospinal fluid diffusivity as a potential neuroimaging marker of brain temperature in multiple sclerosis: a hypothesis and implications.Magnetic resonance imaging · 2015Article
- Advanced MRI unravels the nature of tissue alterations in early multiple sclerosis.Annals of clinical and translational neurology · 2014Article
- The correlation of hippocampal T2-mapping with neuropsychology test in patients with Alzheimer's disease.PloS one · 2013Article
- Automated detection of white matter signal abnormality using T2 relaxometry: application to brain segmentation on term MRI in very preterm infants.NeuroImage · 2013Article
- Multi-modal quantitative MRI investigation of brain tissue neurodegeneration in multiple sclerosis.Journal of magnetic resonance imaging : JMRI · 2012Article
- Human brain atlas-based multimodal MRI analysis of volumetry, diffusimetry, relaxometry and lesion distribution in multiple sclerosis patients and healthy adult controls: implications for understanding the pathogenesis of multiple sclerosis and consolidation of quantitative MRI results in MS.Journal of the neurological sciences · 2012Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Several in vivo quantitative MRI techniques have been proposed as surrogate measures to map iron content in the human brain. The majority of in vivo quantitative MRI iron mapping methods used the age-dependent iron content data based on postmortem data. In this work, we fused atlas-based human brain volumetry obtained on a large cohort of healthy adults using FreeSurfer with T(2) relaxation time measurements. We provide a brain atlas-based T(2) relaxation time map, which was subsequently used along with published postmortem iron content data to obtain a map of iron content in subcortical and cortical gray matter. We have also investigated the sensitivity of the linear model relating transverse relaxation rate with published iron content to the number of regions used. Our work highlights the challenges encountered on using the simple model along with postmortem data to infer iron content in several brain regions where postmortem iron data are scant (e.g., corpus callosum, amygdale).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.