ArticleDocumenta ophthalmologica. Advances in ophthalmology2011
Isolated mesopic rod and cone electroretinograms realized with a four-primary method.
Article in Documenta ophthalmologica. Advances in ophthalmology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- The mesopic negative response (MeNR): a novel approach to assess retinal ganglion cell function within the rod pathway.Documenta ophthalmologica. Advances in ophthalmology · 2025Article
- A Temporal White Noise Analysis for Extracting the Impulse Response Function of the Human Electroretinogram.Translational vision science & technology · 2017Article
- The morphology of human rod ERGs obtained by silent substitution stimulation.Documenta ophthalmologica. Advances in ophthalmology · 2017Article
- Abnormal 8-Hz flicker electroretinograms in carriers of X-linked retinoschisis.Documenta ophthalmologica. Advances in ophthalmology · 2016Article
- Rod Electroretinograms Elicited by Silent Substitution Stimuli from the Light-Adapted Human Eye.Translational vision science & technology · 2016Article
- Rod- and cone-driven responses in mice expressing human L-cone pigment.Journal of neurophysiology · 2015Article
- A method for estimating intrinsic noise in electroretinographic (ERG) signals.Documenta ophthalmologica. Advances in ophthalmology · 2015Article
- Rod and cone contributions to the dark-adapted 15-Hz flicker electroretinogram.Documenta ophthalmologica. Advances in ophthalmology · 2015Article
- A five-primary photostimulator suitable for studying intrinsically photosensitive retinal ganglion cell functions in humans.Journal of vision · 2015Article
- Rod- and cone-isolated flicker electroretinograms and their response summation characteristics.Visual neuroscience · 2015Article
- Human flicker electroretinography using different temporal modulations at mesopic and photopic luminance levels.Documenta ophthalmologica. Advances in ophthalmology · 2014Article
- Assessing rod, cone, and melanopsin contributions to human pupil flicker responses.Investigative ophthalmology & visual science · 2014Article
- Vision under mesopic and scotopic illumination.Frontiers in psychology · 2014Review
- Assessment of "non-recordable" electroretinograms by 9 Hz flicker stimulation under scotopic conditions.Documenta ophthalmologica. Advances in ophthalmology · 2012Article
- Retinal safety and toxicity study of artesunateAdvances in ophthalmology practice and researchArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The purpose of this study was to evaluate the feasibility of measuring rod and cone electroretinograms (ERGs) at a single mesopic adaptation level. To accomplish this, a four-primary photostimulator was implemented using a commercially available ERG system (Diagnosys ColorDome) to generate three types of stimuli that temporally modulated rods alone, cones alone, and rods and cones simultaneously. For each stimulus type, ERGs were recorded as a function of temporal frequency (2, 4, 8, or 16 Hz) and mesopic light levels (0.02, 0.16, or 1.26 cd/m(2)) in normal observers and patients with retinitis pigmentosa (RP) or cone-rod degeneration. The normal observers ERG waveforms showed a clear periodic pattern, mirroring the sinusoidal stimuli. At all light levels, rod responses were always higher than cone responses for temporal frequencies between 2 and 8 Hz, suggesting that rods dominated the responses. Cone responses were minimal at the lowest light level and increased with increases in light level. The amplitude of the response to the combined stimuli was intermediate between that of the isolated cone and the isolated rod stimuli for all light levels. Good receptoral isolation was confirmed by the results showing (1) minimal or no rod ERGs but recordable cone ERGs in the patients and (2) high correlation between the ERG amplitudes obtained from the four-primary method and those from the ISCEV standard clinical protocol in normal observers.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.