Trial reportEuropean journal of pediatrics2012
The effects of detraining on blood adipokines and antioxidant enzyme in Korean overweight children.
Trial report in European journal of pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Effects of exercise on cardiorespiratory fitness in children and adolescents with overweight and obesity: a systematic review and meta-analysis of 72 randomized controlled trials.BMC public health · 2025Pooled it
- Transcriptional and Epigenetic Response to Sedentary Behavior and Physical Activity in Children and Adolescents: A Systematic Review.Frontiers in pediatrics · 2022Pooled it
- Pooled it
- Review
- Impact of exercise on cardiovascular disease risk in overweight or obese children and adolescents: a systematic review and meta-analysis.BMC sports science, medicine & rehabilitation · 2025Article
- Assessing the impact of body composition, metabolic and oxidative stress parameters on insulin resistance as a prognostic marker for reactive hypoglycemia: a cross-sectional study in overweight, obese, and normal weight individuals.Frontiers in pharmacology · 2024Article
- Association between biomarkers of redox status and cytokines with different patterns of habitual physical activity in eutrophic and overweight/obese preschoolers: multivariate analysis of a cross-sectional study.BMC public health · 2023Article
- Exercise Outcomes in Childhood Obesity-Related Inflammation and Oxidative Status.Frontiers in nutrition · 2022Review
- Review
- Total Oxidant and Antioxidant Status in Prepubertal Children with Obesity.Oxidative medicine and cellular longevity · 2017Article
- Effects of regular exercise on obesity and type 2 diabete mellitus in Korean children: improvements glycemic control and serum adipokines level.Journal of physical therapy science · 2015Article
- Oxidative/Antioxidative status in obese and sport trained children: a comparative study.BioMed research international · 2015Article
- Evaluation of oxidant-antioxidant status in overweight and morbidly obese Saudi children.World journal of clinical pediatrics · 2014Article
- Effects of a long-term physical exercise program with and without diet on obese boys after six-month detraining.World journal of pediatrics : WJP · 2014Article
- Effects of exercise and diet change on cognition function and synaptic plasticity in high fat diet induced obese rats.Lipids in health and disease · 2013Article
- Antioxidant enzymes activities in obese Tunisian children.Nutrition journal · 2013Article
- [Metabolic effects of exercise on childhood obesity: a current view].Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao PauloReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study examined the change to clarify the effects of detraining on the concentration of lipid profiles, serum adipokines and antioxidant enzyme gene expression in Korean overweight children. The subjects were normal children (n = 19) and obese children (n = 20) who were further subdivided into the overweight training (OT) group (n = 10) and the overweight detraining (OD) group (n = 10). Maximal oxygen uptake (VO(2)max); body composition; lipid profiles (TG, TC); adipokines (adiponectin and leptin); antioxidants (blood and gene expressions SOD and GPX) were measured before, 12 weeks, and 24 weeks after the exercise program. Body mass index (BMI) and %fat were significantly higher in the OD group only. However, waist hip ration (WHR) and systolic blood pressure (SBP) were significantly decreased in the OT group. TG was significantly decreased in the OT group. There was a significant difference in TG level between the two groups. Besides, adiponectin was significantly increased in both the OT group and the OD group. Furthermore, leptin was significantly decreased in the OT group. There was a significant difference in leptin level between the two groups. In training groups, the expression of SOD was significantly increased after a 12- and 24-week period (p < 0.05). However, detraining group was significantly increased after a 12-week only (p < 0.05). In addition, GPX was significantly increased after a 24-week only in the training group (p < 0.05). Thus, detraining showed that negative effected on body composition and lipid profiles and maintained of uniform period on adipokines and antioxidant enzyme the protein and expression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.