Evidence map›Paper›PMID 21698724›Full record

ArticleAngewandte Chemie (International ed. in English)2011

Differentially charged hollow core/shell lipid-polymer-lipid hybrid nanoparticles for small interfering RNA delivery.

Jinjun Shi, Zeyu Xiao, Alexander R Votruba, Cristian Vilos, Omid C Farokhzad

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Polymeric nanocarriers for therapeutic gene delivery.Asian journal of pharmaceutical sciences · 2025
    Review
  6. Core-Shell Nanoparticles for Pulmonary Drug Delivery.Pharmaceutical nanotechnology · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. DDAB cationic lipid-mPEG, PCL copolymer hybrid nano-carrier synthesis and application for delivery of siRNA targeting IGF-1R into breast cancer cells.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Article
  19. Article
  20. A NovelLife (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jinjun ShiDepartment of Anesthesiology, Brigham and Women's Hospital, Boston, MA 02115, USA.
Zeyu Xiao
Alexander R Votruba
Cristian Vilos
Omid C Farokhzad

Funding

The Development of Clinical Grade, Targeted Magnetic NanoparticlesU54CA151884 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELCHER, ANGELA M. · 2010 to 2014
$11.3M
Development of Disease-Specific Drug Delivery VehiclesK08EB003647 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI FAROKHZAD, OMID C · 2005 to 2009
$964k
NCI NIH HHS CA151884NCI NIH HHS U54 CA151884NHLBI NIH HHS N01 HV-08236NIBIB NIH HHS EB003647NIBIB NIH HHS K08 EB003647
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsHeLa CellsHumansLipidsMiceNanoparticlesNeoplasmsPolymersRNA, Small InterferingLipidsPolymersRNA, Small Interfering

Identifiers

PMID21698724
PMCPMC3515655

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.