Evidence map›Paper›PMID 21698485›Full record

ArticleClinical orthopaedics and related research2011

Women recover faster than men after standard knee arthroplasty.

Thoralf R Liebs, Wolfgang Herzberg, Annette Maria Roth-Kroeger, Wolfgang Rüther, Joachim Hassenpflug

Registry-linked trialOpen access · greenAbstract readComparative Study
In one paragraph

Article in Clinical orthopaedics and related research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00951990 (A Multicenter Randomized Controlled Trail of Ergometer Cycling After Hip and Knee Replacement Surgery), which is not on this map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00951990 phase1 / phase2completednot on this map

A Multicenter Randomized Controlled Trail of Ergometer Cycling After Hip and Knee Replacement Surgery

TypeinterventionalSponsorVerein zur Förderung der Rehabilitationsforschung in Schleswig-HolsteinRan2005 to 2008Enrolled457ConditionsOsteoarthritisArmsErgometer Cycling, No ergometer cycling
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Observational
  5. Risk Factors for Nonresilient Outcomes in Older Adults After Total Knee Replacement.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  6. Article
  7. Article
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  10. Clinical improvement and satisfaction after total joint replacement: a prospective 12-month evaluation on the patients' perspective.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2015
    Article
  11. Article
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  13. Article
  14. Gender differences in the morphology of the trochlea and the distal femur.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2014
    Article
  15. Observational
  16. Article
  17. Article
  18. Mediolateral oversizing influences pain, function, and flexion after TKA.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2013
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Thoralf R LiebsDepartment of Orthopaedic Surgery, University of Schleswig-Holstein Medical Center, Kiel Campus, Michaelisstr 1, 24105 Kiel, Germany. liebs@liebs.eu
Wolfgang Herzberg
Annette Maria Roth-Kroeger
Wolfgang Rüther
Joachim Hassenpflug
BG Klinikum Hamburg · DEUniversität Hamburg · DEUniversity Hospital Schleswig-Holstein · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpecific anatomic differences are believed to account for gender-specific function and health-related quality of life after TKA. However, there are conflicting data in the literature regarding these gender-specific outcomes, especially as woman appear to have surgery later in the course of the disease compared with men. QUESTIONS/PURPOSES: We asked whether (1) women had worse knee function and health-related quality of life after TKA compared with men, (2) lower improvements in scores, and (3) slower recovery after surgery.

methodsUsing a cohort study design, we retrospectively analyzed prospectively collected data from three multicenter randomized controlled trials evaluating rehabilitation measures after standard unisex knee arthroplasty in 494 patients (141 men and 353 women). The primary outcome was self-reported physical function as measured by the WOMAC at 3, 6, 12, and 24 months after surgery. Secondary outcomes included the pain and stiffness scales of the WOMAC and the physical and mental component summaries of the SF-36. At the time of surgery, the women were on average older (70.8 versus 67.8 years), had lower mean physical function (55 versus 47), higher mean pain scores (54 versus 48), and greater stiffness (54 versus 46) as measured by the WOMAC.

resultsAt the 3-, 6-, 12-, and 24-month followups, men and women had similar WOMAC scores. Improvements were greater for women compared with men for WOMAC function and pain subscale scores at the 3-month (function, 28 versus 23; pain, 32 versus 25) and 6-month followups (function, 32 versus 27; pain, 36 versus 31). At the 12- and 24-month followups we noted no differences in improvement between men and women.

conclusionAlthough women had greater functional limitations at the time of surgery than men, they recover faster early after standard TKA although function is similar at 12 and 24 months. Women also had greater improvement of WOMAC scores after standard TKA than men. LEVEL OF EVIDENCE: Level II, prognostic study. See the guidelines for authors for a complete description of levels of evidence.

Indexed as

Arthroplasty, Replacement, KneeHealth Status DisparitiesAgedDisability EvaluationFemaleGermanyHumansKnee JointMaleMiddle AgedMulticenter Studies as TopicPain MeasurementPostoperative PainQuality of LifeRandomized Controlled Trials as TopicRecovery of Function

Identifiers

PMID21698485
PMCPMC3171538
OpenAlexW1982681862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.