ArticleSurgical neurology international2011
Near-infrared spectroscopy monitoring of cerebral oxygen during assisted ventilation.
Article in Surgical neurology international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Different ventilation techniques and hemodynamic optimization to maintain regional cerebral oxygen saturation (rScOJournal of anesthesia · 2018Trial
- Effect of Nasal Continuous Positive Airway Pressure on Retinopathy of Prematurity in Preterm Newborns: A Comparative Analysis with Mechanical Ventilation and High-Flow Nasal Cannula Therapy.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Effect of the change of mechanical ventilation mode on cerebral oxygen saturation level in neonates.BMC pediatrics · 2023Observational
- A phase-II clinical trial of targeted cerebral near infrared spectroscopy using standardized treatment guidelines to improve brain oxygenation in preterm infants (BOx-II): A study protocol.Contemporary clinical trials · 2022Article
- A cervical compartment syndrome impairs cerebral circulation in post-thyroidectomy hemorrhage: data from an animal model.Gland surgery · 2022Article
- Study of the relationship between regional cerebral saturation and pCO2 changes during mechanical ventilation to evaluate modifications in cerebral perfusion in a newborn piglet model.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022Article
- Parameters Influencing Brain Oxygen Measurement by Regional Oxygen Saturation in Postcardiac Arrest Patients with Targeted Temperature Management.Therapeutic hypothermia and temperature management · 2020Observational
- Respiratory Care for the Ventilated Neonate.Canadian respiratory journal · 2018Review
- Changes in cerebral oxygenation based on intraoperative ventilation strategy.Medical devices (Auckland, N.Z.) · 2018Article
- Changes in Near-Infrared Spectroscopy After Congenital Cyanotic Heart Surgery.Frontiers in pediatrics · 2018Article
- Cerebral Autoregulation, Brain Injury, and the Transitioning Premature Infant.Frontiers in pediatrics · 2017Review
- Changes in regional tissue oxygenation saturation and desaturations after red blood cell transfusion in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2013Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChanges in the arterial partial pressure of CO(2) (PaCO(2)) has a direct though transient effect on the cerebral vasculature and cerebral circulation. Decreased PaCO(2) levels lead to vasoconstriction and can result in dangerously low levels of cerebral perfusion that resolve in 4-6 h. It is currently believed that perfusion abnormalities contribute to intraventricular hemorrhage (IVH) and periventricular leukomalacia (PVL) in the neonate. PaCO(2)-induced vasoconstriction may contribute to the pathology of IVH and PVL.
methodsNear-infrared spectroscopy [NIRS; (INVOS cerebral/somatic oximeter; Somanetics Corporation, Troy, MI, USA)] was utilized to determine changes in regional oxygenation (rSO(2)) of the brain in response to changes in ventilation in isoflurane anesthetized newborn piglets.
resultsChanges in cerebral rSO(2) correlated significantly with end-tidal CO(2) levels and to blood flow in the common carotid artery. This correlation was significant during baseline conditions, after periods of CO(2) loading and during periods of hypothermia.
conclusionsThe results of the study demonstrate the utility of NIRS to accurately reflect changes in cerebral oxygenation and flow to the brain in response to changes in CO(2) levels in anesthetized, ventilated neonatal piglets. The use of NIRS may provide an early alert of low levels of cerebral blood flow and brain oxygenation, potentially helping in preventing the progression of IVH or PVL in the neonate.
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