ArticleJournal of clinical microbiology2011
Extensive horizontal gene transfer in ureaplasmas from humans questions the utility of serotyping for diagnostic purposes.
Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed.
- The Impact of Intrauterine Devices on the Risk of Ureaplasma Species Overgrowth: A Review of the Literature.Cureus · 2025Review
- Characterization of cervical fluid Ureaplasma species in pregnant women with spontaneous preterm delivery.Scientific reports · 2025Article
- Detection ofFrontiers in cellular and infection microbiology · 2025Article
- Could APTIMA mRNA Assay Contribute to Predicting Cervical Bacterial Sexually Transmitted Co-Infections? A Colposcopy Population Study.International journal of molecular sciences · 2024Article
- Cervical HPV Infections, Sexually Transmitted Bacterial Pathogens and Cytology Findings-A Molecular Epidemiology Study.Pathogens (Basel, Switzerland) · 2023Article
- Association between human papillomavirus infection and common sexually transmitted infections, and the clinical significance of differentFrontiers in cellular and infection microbiology · 2023Article
- Genome Mosaicism in Field Strains of Mycoplasma bovis as Footprints of In-Host Horizontal Chromosomal Transfer.Applied and environmental microbiology · 2022Article
- Prevalence and Load of Cervical Ureaplasma Species With Respect to Intra-amniotic Complications in Women With Preterm Prelabor Rupture of Membranes Before 34 weeks.Frontiers in pharmacology · 2022Article
- Aetiology and prevalence of mixed-infections and mono-infections in non-gonococcal urethritis in men: a case-control study.Sexually transmitted infections · 2020Article
- Detection ofInfectious diseases in obstetrics and gynecology · 2020Article
- Detection of Ureaplasma spp. serovars in genital tract of infertile males.Journal of clinical laboratory analysis · 2019Article
- Mycoplasma Chromosomal Transfer: A Distributive, Conjugative Process Creating an Infinite Variety of Mosaic Genomes.Frontiers in microbiology · 2019Article
- Differential modulation of pulmonary caspases: Is this the key to Ureaplasma-driven chronic inflammation?PloS one · 2019Article
- PerinatalFrontiers in cellular and infection microbiology · 2019Article
- Mycoplasmas under experimental antimicrobial selection: The unpredicted contribution of horizontal chromosomal transfer.PLoS genetics · 2019Article
- Ureaplasma urealyticum and U. parvum in sexually active women attending public health clinics in Brazil.Epidemiology and infection · 2017Article
- The Human Ureaplasma Species as Causative Agents of Chorioamnionitis.Clinical microbiology reviews · 2017Review
- Ureaplasma parvum genotype, combined vaginal colonisation with Candida albicans, and spontaneous preterm birth in an Australian cohort of pregnant women.BMC pregnancy and childbirth · 2016Article
- Found and Lost: The Fates of Horizontally Acquired Genes in Arthropod-Symbiotic Spiroplasma.Genome biology and evolution · 2015Article
- Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Ureaplasma parvum and Ureaplasma urealyticum are sexually transmitted, opportunistic pathogens of the human urogenital tract. There are 14 known serovars distributed between the two species. For decades, it has been postulated based upon limited data that virulence is related to serotype specificity. The results were often inconclusive due to the small sample size and extensive cross-reactivity between certain serovars. We developed real-time quantitative PCRs that allow reliable differentiation of the two species and type strains of each of the 14 serovars. To investigate species and serovar distributions, we typed 1,061 clinical isolates of human ureaplasmas from diverse patient populations. There was only a tenuous association between individual Ureaplasma serovars and certain patient populations. This may in part be explained by the fact that almost 40% of the isolates were genetic mosaics, apparently arising from the recombination of multiple serovars. This explains the extensive cross-reactivity based upon serotyping and the lack of consistent association of given serotypes with disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.