ReviewTrends in neurosciences2011
Historical and current perspective on tobacco use and nicotine addiction.
Review in Trends in neurosciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Structural insights into the progressive recovery of α7 nicotinic acetylcholine receptor from nicotine-induced desensitization.Science advances · 2025Article
- The effects of electronic nicotine vapor on voluntary alcohol consumption in female and male C57BL/6 J mice.Drug and alcohol dependence · 2022Article
- Article
- Adolescent nicotine administration increases nicotinic acetylcholine receptor binding and functional connectivity in specific cortico-striatal-thalamic circuits.Brain communications · 2022Article
- Multifactorial Etiology of Adolescent Nicotine Addiction: A Review of the Neurobiology of Nicotine Addiction and Its Implications for Smoking Cessation Pharmacotherapy.Frontiers in public health · 2021Review
- The ecology of multilevel intervention research.Translational behavioral medicine · 2018Article
- A Drosophila model for developmental nicotine exposure.PloS one · 2017Article
- TC299423, a Novel Agonist for Nicotinic Acetylcholine Receptors.Frontiers in pharmacology · 2017Article
- Small Heat Shock Proteins Are Novel Common Determinants of Alcohol and Nicotine Sensitivity in Caenorhabditis elegans.Genetics · 2016Article
- Belief about Nicotine Modulates Subjective Craving and Insula Activity in Deprived Smokers.Frontiers in psychiatry · 2016Article
- Adolescent Maturational Transitions in the Prefrontal Cortex and Dopamine Signaling as a Risk Factor for the Development of Obesity and High Fat/High Sugar Diet Induced Cognitive Deficits.Frontiers in behavioral neuroscience · 2016Review
- Nicotine and the adolescent brain.The Journal of physiology · 2015Review
- Belief about nicotine selectively modulates value and reward prediction error signals in smokers.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Article
- Neuronal Nicotinic Acetylcholine Receptor Structure and Function and Response to Nicotine.International review of neurobiology · 2015Review
- BDNF/TRK/KCC2 pathway in nicotine withdrawal-induced hyperalgesia.Translational neuroscience · 2015Article
- Resting state functional connectivity of the basal nucleus of Meynert in humans: in comparison to the ventral striatum and the effects of age.NeuroImage · 2014Article
- Cholinergic modulation of the medial prefrontal cortex: the role of nicotinic receptors in attention and regulation of neuronal activity.Frontiers in neural circuits · 2014Review
- Varenicline and cytisine diminish the dysphoric-like state associated with spontaneous nicotine withdrawal in rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2014Article
- Influence of δ-opioid receptors in the behavioral effects of nicotine.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Although the addictive influence of tobacco was recognized very early, the modern concepts of nicotine addiction have relied on knowledge of cholinergic neurotransmission and nicotinic acetylcholine receptors (nAChRs). The discovery of the 'receptive substance' by Langley, that would turn out to be nAChRs, and 'Vagusstoff' (acetylcholine) by Loewi, coincided with an exciting time when the concept of chemical synaptic transmission was being formulated. More recently, the application of more powerful techniques and the study of animal models that replicate key features of nicotine dependence have led to important advancements in our understanding of molecular, cellular and systems mechanisms of nicotine addiction. In this review, we present a historical perspective and overview of the research that has led to our present understanding of nicotine addiction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.