Evidence map›Paper›PMID 21696632›Full record

ArticleEnvironmental health : a global access science source2011

Temporal trends in serum concentrations of polychlorinated dioxins, furans, and PCBs among adult women living in Chapaevsk, Russia: a longitudinal study from 2000 to 2009.

Olivier Humblet, Oleg Sergeyev, Larisa Altshul, Susan A Korrick, Paige L Williams, Claude Emond, Linda S Birnbaum, Jane S Burns, Mary M Lee, Boris Revich and 3 more

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 3 countries.

Olivier HumbletEnvironmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA.
Oleg Sergeyev
Larisa Altshul
Susan A Korrick
Paige L Williams
Claude Emond
Linda S Birnbaum
Jane S Burns
Mary M Lee
Boris Revich
Andrey Shelepchikov
Denis Feshin
Russ Hauser
Boston University · USHarvard University · USSevertsov Institute of Ecology and Evolution · RUInstitute of Economic Forecasting · RUNational Cancer Institute · USSamara State Medical University · RUUniversité de Montréal · CAUniversity of Massachusetts Chan Medical School · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
PILOT AND FEASIBILITY PROGRAMP30DK032520 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI CZECH, MICHAEL P · 1986 to 2010
$14.6M
Training Program in Environmental EpidemiologyT32ES007069 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LADEN, FRANCINE · 1985 to 2024
$13.9M
Effects of Environmental Phthalates and Chemical Mixtures on Male Puberty and Semen QualityR01ES014370 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI HAUSER, RUSS B · 2006 to 2021
$8.2M
Interdisciplinary Training in Genes and the EnvironmentT32ES016645 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI LEE, CHIH-HAO · 2008 to 2018
$4.0M
Maternal Pesticide Exposure and Pregnancy OutcomesR01ES013967 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI HAUSER, RUSS B · 2006 to 2009
$2.1M
NIDDK NIH HHS DK32520NIEHS NIH HHS 5T32ES016645-02NIEHS NIH HHS 5T32-ES07069-28NIEHS NIH HHS ES00002NIEHS NIH HHS ES014370NIEHS NIH HHS R01 ES013967
6 · The paper itself

Abstract

backgroundThe present study assessed the temporal trend in serum concentrations of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls (PCBs) among residents of a Russian town where levels of these chemicals are elevated due to prior industrial activity.

methodsTwo serum samples were collected from eight adult women (in 2000 and 2009), and analyzed with gas chromatography-high-resolution mass spectrometry.

resultsThe average total toxic equivalency (TEQ) decreased by 30% (from 36 to 25 pg/g lipid), and the average sum of PCB congeners decreased by 19% (from 291 to 211 ng/g lipid). Total TEQs decreased for seven of the eight women, and the sum of PCBs decreased for six of eight women. During this nine year period, larger decreases in serum TEQs and PCBs were found in women with greater increases in body mass index.

conclusionsThis study provides suggestive evidence that average serum concentrations of dioxins, furans, and PCBs are decreasing over time among residents of this town.

Indexed as

Environmental ExposureAdultBenzofuransDioxinsEnvironmental PollutantsFemaleGas Chromatography-Mass SpectrometryHumansLongitudinal StudiesPolychlorinated BiphenylsRussiaYoung AdultBenzofuransdibenzofuranDioxinsEnvironmental PollutantsPolychlorinated Biphenyls

Identifiers

PMID21696632
PMCPMC3142486
OpenAlexW2121568255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.