Evidence map›Paper›PMID 21695733›Full record

ArticleHuman psychopharmacology

Concomitant medication of psychoses in a lifetime perspective.

Maria Vares, Peter Saetre, Pontus Strålin, Sten Levander, Eva Lindström, Erik G Jönsson

Abstract read
In one paragraph

Article in Human psychopharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Prescription patterns for patients with schizophrenia in Korea: a focus on antipsychotic polypharmacy.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2014
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria VaresDepartment of Clinical Neuroscience, Karolinska Institutet and Hospital, Stockholm, Sweden.
Peter Saetre
Pontus Strålin
Sten Levander
Eva Lindström
Erik G Jönsson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePatients treated with antipsychotic drugs often receive concomitant psychotropic compounds. Few studies address this issue from a lifetime perspective. Here, an analysis is presented of the prescription pattern of such concomitant medication from the first contact with psychiatry until the last written note in the case history documents, in patients with a diagnosis of psychotic illness.

methodsA retrospective descriptive analysis of all case history data of 66 patients diagnosed with schizophrenia or schizophrenia-like psychotic disorders.

resultsBenzodiazepines and benzodiazepine-related anxiolytic drugs had been prescribed to 95% of the patients, other anxiolytics, sedatives or hypnotic drugs to 61%, anti-parkinsonism drugs to 86%, and antidepressants to 56% of the patients. However, lifetime doses were small and most of the time patients had no concomitant medication. The prescribed lifetime dose of anti-parkinsonism drugs was associated with that of prescribed first-generation but not second-generation antipsychotics.

conclusionsMost psychosis patients are sometimes treated with concomitant drugs but mainly over short periods. Lifetime concomitant add-on medication at the individual patient level is variable and complex but not extensive.

Indexed as

AdultAnti-Anxiety AgentsAntidepressive AgentsAntiparkinson AgentsAntipsychotic AgentsDiagnostic and Statistical Manual of Mental DisordersDrug Therapy, CombinationFemaleHospitals, UrbanHumansHypnotics and SedativesMaleMiddle AgedOutpatient Clinics, HospitalPsychotic DisordersPsychotropic DrugsAnti-Anxiety AgentsAntidepressive AgentsAntiparkinson AgentsAntipsychotic AgentsHypnotics and SedativesPsychotropic Drugs

Identifiers

PMID21695733
PMCPMC3505368

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.