Evidence map›Paper›PMID 21695465›Full record

SynthesisKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2012

Collagen meniscus implantation: a systematic review including rehabilitation and return to sports activity.

Andrew Harston, John Nyland, Emily Brand, Mark McGinnis, David N M Caborn

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. MRI evaluation of a collagen meniscus implant: a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2015
    Pooled it
  2. Collagen-Based Scaffolds for Meniscal Repair and Regeneration.Journal of tissue engineering and regenerative medicine · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Autologous semitendinosus tendon graft could function as a meniscal transplant.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022
    Article
  7. Article
  8. Review
  9. Ongoing MRI remodeling 3-7 years after collagen meniscus implantation in stable knees.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Advances in regenerative orthopedics.Mayo Clinic proceedings · 2013
    Article
  15. Consideration of religious sentiments while selecting a biological product for knee arthroscopy.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2013
    Review
  16. Article
  17. Article
  18. Article
  19. Collagen Type I: A Versatile Biomaterial.Advances in experimental medicine and biology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Andrew HarstonDivision of Sports Medicine, Department of Orthopaedic Surgery, University of Louisville, 210 East Gray Street, Suite 1003, Louisville, KY 40202, USA.
John Nyland
Emily Brand
Mark McGinnis
David N M Caborn
University of Louisville · USUniversity of Louisville Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine collagen meniscus implant (CMI) efficacy for improving patient function, symptoms, and activity level. Study methodologies, rehabilitation, and return to sports guidelines were also reviewed.

methodsMedLine, EMBASE, CINAHL, Life Science Citations, and Cochrane Central Register of Controlled Trials databases were searched from January 1995-May 2011 using the term collagen meniscal or meniscus implant. Only human studies with English language abstracts that reported patient outcomes were included. Modified Coleman Methodology criteria were used to score research quality.

resultsEleven studies with 520 subjects (men = 428; women = 92; 17.7% women) of 38.2 ± 3.7 years of age met the inclusion criteria. Of these subjects, 321 (men = 263, women = 58; 18.1% women) received a CMI. Based primarily on Lysholm Knee Score, Tegner Activity Scale, pain scales and self-assessment measurements knee function, symptoms, and activity level generally improved by 46.6 ± 39.9 months post-surgery. Rehabilitation was described in 9/11 (81.8%) studies and four released patients to full activities at 6 months post-surgery. No study described how advanced rehabilitation or function testing contributed to return to activity decision-making. Research quality was generally low (67.1 ± 18.6) with widely ranging (29-97) scores. Reduced CMI size at last follow-up was reported in 6/11 (54.5%) studies, but the significance of this finding is unknown.

conclusionsKnee function, symptoms, and activity level generally improved following CMI use, but poor research report quality was common. Additional well-designed long-term prospective studies are needed to better determine knee osteoarthrosis prevention efficacy and appropriate patient selection.

Indexed as

Collagen Type ISurgical MeshArthroplastyAthletic InjuriesGuided Tissue RegenerationHumansKnee InjuriesMenisci, TibialPractice Guidelines as TopicRecovery of FunctionTibial Meniscus InjuriesTreatment OutcomeCollagen Type I

Identifiers

PMID21695465
OpenAlexW1968463141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.