Evidence map›Paper›PMID 21694907›Full record

ArticleInfection and drug resistance2011

Management of refractory Pseudomonas aeruginosa infection in cystic fibrosis.

Roger Sordé, Albert Pahissa, Jordi Rello

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Article
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  5. Article
  6. Substrate-Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors.Angewandte Chemie (International ed. in English) · 2022
    Article
  7. Antibiotics (Basel, Switzerland) · 2021
    Review
  8. Quantitative proteomic reveals gallium maltolate induces an iron-limited stress response and reduced quorum-sensing in Pseudomonas aeruginosa.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2020
    Article
  9. Antimicrobial Properties of the Polyaniline Composites againstJournal of functional biomaterials · 2020
    Article
  10. Journal of medicinal chemistry · 2020
    Article
  11. TheMolecular & cellular proteomics : MCP · 2020
    Article
  12. Minimum Bactericidal Concentration of Ciprofloxacin toSensors and actuators. B, Chemical · 2020
    Article
  13. Characterization of Putative Virulence Factors ofBioMed research international · 2020
    Article
  14. Article
  15. Quorum Sensing as Antivirulence Target in Cystic Fibrosis Pathogens.International journal of molecular sciences · 2019
    Review
  16. Pyoverdine-Dependent Virulence ofFrontiers in microbiology · 2019
    Article
  17. Targeting theBeilstein journal of organic chemistry · 2018
    Review
  18. Article
  19. Article
  20. Distribution ofJournal of preventive medicine and hygiene · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Roger SordéDepartment of Infectious Diseases, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain;
Albert Pahissa
Jordi Rello
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESRed Espanola de Investigacion en Patologia Infecciosa · ESVall d'Hebron Institut de Recerca · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic fibrosis (CF) is the most common life-limiting inherited disease in Caucasian populations. The main cause of death in CF patients is respiratory failure resulting from chronic pulmonary infection. Pseudomonas aeruginosa is the most prevalent organism in the airway colonization of CF patients, and its persistence in the airways has been related to greater morbidity with a more rapid deterioration in lung function. P. aeruginosa has enormous genetic and metabolic flexibility that allows it to adapt and persist within the airways of CF patients, and it has the ability to easily acquire antimicrobial resistance. For these reasons, the management of infections and chronic colonization by P. aeruginosa remains a challenge for physicians. This article reviews the current and future antibacterial chemotherapy options for respiratory pseudomonal infection in CF patients.

Indexed as

antimicrobial treatmentcystic fibrosisPseudomonas aeruginosarespiratory infection

Identifiers

PMID21694907
PMCPMC3108754
OpenAlexW2065372703

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.