ArticleClinical and experimental gastroenterology2010
Acute gastroenteritis: from guidelines to real life.
Article in Clinical and experimental gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05876585 (A Randomized, Double-Blinded, Placebo-Controlled, Phase III Clinical Trial to Investigate the Efficacy and Safety of Ondansetron), which is not on this map. Cited by 54 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized, Double-Blinded, Placebo-Controlled, Phase III Clinical Trial to Investigate the Efficacy and Safety of Ondansetron (Danset - Adwia) Versus Placebo Plus the Standard of Care in the Treatment of Nausea and Vomiting in Adult Patients With Acute Gastroenteritis
Who cites it
54 citing papers in PubMed, 4 syntheses or guidelines pooled it, 138 citations in OpenAlex.
- Systematic review of point-of-need molecular diagnostics for rotavirus and enteric adenoviruses F40/F41.BMC infectious diseases · 2026Pooled it
- The Impact ofInternational journal of environmental research and public health · 2024Pooled it
- Enteric pathogens associated with gastroenteritis among children under 5 years in sub-Saharan Africa: a systematic review and meta-analysis.Epidemiology and infection · 2020Pooled it
- Haloperidol for the treatment of nausea and vomiting in palliative care patients.The Cochrane database of systematic reviews · 2015Pooled it
- Oral ondansetron for paediatric gastroenteritis in primary care: a randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021Trial
- Cost-effectiveness of oral ondansetron for children with acute gastroenteritis in primary care: a randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021Trial
- Ondansetron treatment reduces rotavirus symptoms-A randomized double-blinded placebo-controlled trial.PloS one · 2017Trial
- Resolution of acute gastroenteritis symptoms in children and adults treated with a novel polyphenol-based prebiotic.World journal of gastroenterology · 2014Trial
- Syndromic surveillance systems to detect outbreaks of gastroenteritis in high-income countries: a scoping review.BMC public health · 2026Article
- Diarrhea management: from pathophysiology to microbiota modulation.Therapeutic advances in gastroenterology · 2026Review
- Whole genome sequence analysis of multidrug-resistant Salmonella enterica Typhimurium ms203 provides insights into virulence and antibiotic resistance.Current genetics · 2025Article
- The current state of pediatric gastroenterology in under-resourced nations.Annals of medicine and surgery (2012) · 2025Review
- Comparison of AccuPower Diarrhea V1&V2 RT-PCR to a Chromatographic Immunoassay for Detecting Viral Pathogens from Human Diarrheal Stool Specimens.Tropical medicine and infectious disease · 2025Article
- Electrolyte abnormalities and clinical outcomes in children aged one month to 13 years hospitalized with acute gastroenteritis in two large referral hospitals in Botswana.PLOS global public health · 2025Article
- Enablers and Barriers to Home Management for Children with Gastroenteritis: Systematic Review.Journal of pediatrics. Clinical practice · 2024Article
- Impact ofNutrients · 2024Review
- Association between detection rate of norovirus GII and climatic factors in the Northwest Amazon region.Heliyon · 2024Article
- Health Care Utilization and Clinical Management of All-Cause and Norovirus-Associated Acute Gastroenteritis Within a US Integrated Health Care System.Open forum infectious diseases · 2024Article
- Comparing healthcare systems between the Netherlands and Australia in management for children with acute gastroenteritis.PloS one · 2024Article
- The Emergence and Widespread Circulation of Enteric Viruses Throughout the COVID-19 Pandemic: A Wastewater-Based Evidence.Food and environmental virology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute gastroenteritis is a very common disease. It causes significant mortality in developing countries and significant economic burden to developed countries. Viruses are responsible for approximately 70% of episodes of acute gastroenteritis in children and rotavirus is one of the best studied of these viruses. Oral rehydration therapy is as effective as intravenous therapy in treating mild to moderate dehydration in acute gastroenteritis and is strongly recommended as the first line therapy. However, the oral rehydration solution is described as an underused simple solution. Vomiting is one of the main reasons to explain the underuse of oral rehydration therapy. Antiemetics are not routinely recommended in treating acute gastroenteritis, though they are still commonly prescribed. Ondansetron is one of the best studied antiemetics and its role in enhancing the compliance of oral rehydration therapy and decreasing the rate of hospitalization has been proved recently. The guidelines regarding the recommendation on antiemetics have been changed according to the evidence of these recent studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.