Evidence map›Paper›PMID 21694816›Full record

ArticleTherapeutic advances in neurological disorders2011

Symptomatic therapy in multiple sclerosis: a review for a multimodal approach in clinical practice.

João Carlos Correia de Sa, Laura Airas, Emmanuel Bartholome, Nikolaos Grigoriadis, Heinrich Mattle, Celia Oreja-Guevara, Jonathan O'Riordan, Finn Sellebjerg, Bruno Stankoff, Karl Vass and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Therapeutic advances in neurological disorders, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 93 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Observational
  5. Article
  6. Review
  7. Review
  8. Ontology for Symptomatic Treatment of Multiple Sclerosis.Healthcare informatics research · 2022
    Article
  9. Article
  10. Article
  11. Review
  12. The Wahls Behavior Change Model for Complex Chronic Diseases: A Clinician's Guide.Degenerative neurological and neuromuscular disease · 2022
    Article
  13. Article
  14. Perspectives on urological care in multiple sclerosis patients.Intractable & rare diseases research · 2021
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Reliability and validity of the Eating Assessment Tool-10 (Greek adaptation) in neurogenic and head and neck cancer-related oropharyngeal dysphagia.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 12 institutions in 11 countries.

João Carlos Correia de SaHospital de Santa Maria, Lisbon, Portugal.
Laura Airas
Emmanuel Bartholome
Nikolaos Grigoriadis
Heinrich Mattle
Celia Oreja-Guevara
Jonathan O'Riordan
Finn Sellebjerg
Bruno Stankoff
Karl Vass
Agata Walczak
Heinz Wiendl
Bernd C Kieseier
AHEPA University Hospital · GRAssistance Publique – Hôpitaux de Paris · FRCentre Hospitalier Universitaire de Tivoli · BECopenhagen University Hospital · DKHeinrich Heine University Düsseldorf · DEHospital de Santa Maria · PTMedical University of Lodz · PLNHS Tayside · GBTurku University Hospital · FIUniversity Hospital of Bern · CHUniversity of Münster · DEUniversity of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As more investigations into factors affecting the quality of life of patients with multiple sclerosis (MS) are undertaken, it is becoming increasingly apparent that certain comorbidities and associated symptoms commonly found in these patients differ in incidence, pathophysiology and other factors compared with the general population. Many of these MS-related symptoms are frequently ignored in assessments of disease status and are often not considered to be associated with the disease. Research into how such comorbidities and symptoms can be diagnosed and treated within the MS population is lacking. This information gap adds further complexity to disease management and represents an unmet need in MS, particularly as early recognition and treatment of these conditions can improve patient outcomes. In this manuscript, we sought to review the literature on the comorbidities and symptoms of MS and to summarize the evidence for treatments that have been or may be used to alleviate them.

Indexed as

clinical medicinecomorbiditymultiple sclerosisneurologyreviewsigns and symptomstherapy

Identifiers

PMID21694816
PMCPMC3105633
OpenAlexW2114111592

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.