ArticleTherapeutic advances in gastroenterology2011
Probiotics in the prevention of antibiotic-associated diarrhoea and Clostridium difficile infection.
Article in Therapeutic advances in gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review: probiotics in the management of lower gastrointestinal symptoms in clinical practice -- an evidence-based international guide.Alimentary pharmacology & therapeutics · 2013Pooled it
- Trial
- A multicentre randomised controlled trial evaluating lactobacilli and bifidobacteria in the prevention of antibiotic-associated diarrhoea in older people admitted to hospital: the PLACIDE study protocol.BMC infectious diseases · 2012Trial
- Open-label trial of a multi-strain synbiotic in cats with chronic diarrhea.Journal of feline medicine and surgery · 2012Trial
- Three Characterized Probiotics from Dairy Sources-Weissella confusa (ProY 5.1), Enterococcus lactis (ProY 5.3), and Leuconostoc lactis (RM 2.1)-Exhibit Potential for Antidiarrheal Effects.Probiotics and antimicrobial proteins · 2026Article
- Link between physical activity, nutrition, and antimicrobial pharmacokinetics and therapeutic efficacy: Implications for resistance management.SAGE open medicine · 2026Review
- The global burden and trend of Clostridioides difficile and its association with world antibiotic consumption, 1990-2019.Journal of global health · 2024Article
- Probiotics in Orthopedics: From Preclinical Studies to Current Applications and Future Perspective.Microorganisms · 2023Review
- Role of probiotics in preventingFrontiers in medicine · 2023Review
- In vitro evaluation of probiotic potential and enzymatic profiling of Pichia kudriavzevii Y33 isolated from traditional home-made mango pickle.Journal, genetic engineering & biotechnology · 2022Article
- Rifaximin Therapy for Patients With Metronidazole-Unresponsive Clostridium difficile Infection.Cureus · 2022Article
- DietaryExperimental and therapeutic medicine · 2021Article
- Predictive factors, outcomes, and molecular epidemiology of Clostridioides difficile diarrhea in Brazilian hospitals.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Observational
- Therapeutic efficacy of probioticHeliyon · 2021Article
- Bovine Lactoferrin in the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial.Frontiers in pediatrics · 2021Article
- Neuropathy in COVID-19 associated with dysbiosis-related inflammation.Turkish journal of biology = Turk biyoloji dergisi · 2021Review
- Utilizing Probiotics for the Prevention and Treatment of Gastrointestinal Diseases.Frontiers in microbiology · 2021Review
- In Vitro Evaluation of Probiotic Potential and Safety Assessment of Lactobacillus mucosae Strains Isolated from Donkey's Lactation.Probiotics and antimicrobial proteins · 2020Article
- RapidACS infectious diseases · 2020Article
- Bacteriocins From LAB and Other Alternative Approaches for the Control ofFrontiers in bioengineering and biotechnology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diarrhoea, as a common side effect of antibiotics, increases treatment costs and length of stay in acute healthcare facilities. One potential strategy to prevent this side effect is the concurrent use of probiotic bacteria or yeast. This review discusses the evidence for the efficacy of probiotics in the prevention of antibiotic-associated diarrhoea and Clostridium difficile infection; the potential mechanisms by which probiotics may work; their safety; what future research is required; and recommendations for use in clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.