Evidence map›Paper›PMID 21693046›Full record

ReviewReproductive biology and endocrinology : RB&E2011

Aromatase inhibitors in men: effects and therapeutic options.

Willem de Ronde, Frank H de Jong

Open access · goldAbstract readReview
In one paragraph

Review in Reproductive biology and endocrinology : RB&E, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 3 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 3 syntheses or guidelines pooled it, 152 citations in OpenAlex.

  1. Pooled it
  2. Aromatase inhibitors for short stature in male children and adolescents.The Cochrane database of systematic reviews · 2015
    Pooled it
  3. Pooled it
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  20. Nutritional aphrodisiacs: Biochemistry and Pharmacology.Current research in food science · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Willem de RondeDepartment of Internal Medicine, Erasmus university Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Frank H de Jong
Erasmus MC · NLSpaarne Gasthuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aromatase inhibitors effectively delay epiphysial maturation in boys and improve testosterone levels in adult men Therefore, aromatase inhibitors may be used to increase adult height in boys with gonadotropin-independent precocious puberty, idiopathic short stature and constitutional delay of puberty. Long-term efficacy and safety of the use of aromatase inhibitors has not yet been established in males, however, and their routine use is therefore not yet recommended.

Indexed as

AdolescentAromatase InhibitorsBody HeightBone DevelopmentBreastChildGrowth DisordersHumansMaleObesityPubertyPuberty, PrecociousSpermatogenesisTestosteroneAromatase InhibitorsTestosterone

Identifiers

PMID21693046
PMCPMC3143915
OpenAlexW2104663096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.