Evidence map›Paper›PMID 21691341›Full record

Trial reportThe American journal of gastroenterology2011

Mindfulness training reduces the severity of irritable bowel syndrome in women: results of a randomized controlled trial.

Susan A Gaylord, Olafur S Palsson, Eric L Garland, Keturah R Faurot, Rebecca S Coble, J Douglas Mann, William Frey, Karyn Leniek, William E Whitehead

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05083091 (Smartphone Stress Management Training for Irritable Bowel Syndrome), which is not on this map. Cited by 111 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 16 pooled it
27.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05083091 nacompletednot on this mapstarted 2022, after this paper: background citation

Smartphone Stress Management Training for Irritable Bowel Syndrome

TypeinterventionalSponsorCarnegie Mellon UniversityRan2022 to 2025Enrolled359ConditionsIrritable Bowel SyndromeArmsMindfulness and Attention Training, Mindfulness training, Coping Condition
3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 16 syntheses or guidelines pooled it, 279 citations in OpenAlex.

  1. Guideline
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  7. Potential Benefit With Complementary and Alternative Medicine in Irritable Bowel Syndrome: A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2021
    Pooled it
  8. Pooled it
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  11. Mindfulness Meditation for Chronic Pain: Systematic Review and Meta-analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2017
    Pooled it
  12. Pooled it
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  16. Acupuncture for treatment of irritable bowel syndrome.The Cochrane database of systematic reviews · 2012
    Pooled it
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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Susan A GaylordProgram on Integrative Medicine, Department of Physical Medicine and Rehabilitation, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, 27599-7200, USA. E-mail: gaylords@med.unc.edu
Olafur S Palsson
Eric L Garland
Keturah R Faurot
Rebecca S Coble
J Douglas Mann
William Frey
Karyn Leniek
William E Whitehead
University of North Carolina at Chapel Hill · USFlorida State University · USOctober 6 University · EG

Funding

UNC Research Fellowship in Complementary and Alternative MedicineT32AT003378 · NCCIH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Keturah Ruth Faurot, Susan Gaylord · 2007 to 2026
$7.8M
PSYCHOPHYSIOLOGY OF IRRITABLE BOWEL SYNDROMER01DK031369 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WHITEHEAD, WILLIAM E · 1986 to 2012
$6.3M
Gastrointestinal Biopsychosocial Research CenterR24DK067674 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WHITEHEAD, WILLIAM E · 2004 to 2008
$4.5M
Craniosacral Therapy in Migraine Feasibility StudyR21AT002750 · NCCIH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MANN, JOHN DOUGLAS · 2006 to 2007
$576k
Mindfulness for Irritable Bowel SyndromeR21AT003619 · NCCIH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GAYLORD, SUSAN · 2006 to 2008
$571k
NCCIH NIH HHS R21 AT002750NCCIH NIH HHS R21 AT003619NCCIH NIH HHS T32 AT003378NIDDK NIH HHS R01 DK031369NIDDK NIH HHS R24 DK067674
6 · The paper itself

Abstract

objectivesThis prospective, randomized controlled trial explored the feasibility and efficacy of a group program of mindfulness training, a cognitive-behavioral technique, for women with irritable bowel syndrome (IBS). The technique involves training in intentionally attending to present-moment experience and non-judgmental awareness of body sensations and emotions.

methodsSeventy-five female IBS patients were randomly assigned to eight weekly and one half-day intensive sessions of either mindfulness group (MG) training or a support group (SG). Participants completed the IBS severity scale (primary outcome), IBS-quality of life, brief symptom inventory-18, visceral sensitivity index, treatment credibility scale, and five-facet mindfulness questionnaire before and after treatment and at 3-month follow-up.

resultsWomen in the MG showed greater reductions in IBS symptom severity immediately after training (26.4% vs. 6.2% reduction; P=0.006) and at 3-month follow-up (38.2% vs. 11.8%; P=0.001) relative to SG. Changes in quality of life, psychological distress, and visceral anxiety were not significantly different between groups immediately after treatment, but evidenced significantly greater improvements in the MG than in the SG at the 3-month follow-up. Mindfulness scores increased significantly more in the MG after treatment, confirming effective learning of mindfulness skills. Participants' ratings of the credibility of their assigned interventions, measured after the first group session, were not different between groups.

conclusionsThis randomized controlled trial demonstrated that mindfulness training has a substantial therapeutic effect on bowel symptom severity, improves health-related quality of life, and reduces distress. The beneficial effects persist for at least 3 months after group training.

Indexed as

AdultAnalysis of VarianceCognitive Behavioral TherapyEmotionsFemaleHumansIrritable Bowel SyndromeMiddle AgedQuality of LifeSelf-Help GroupsSensationSeverity of Illness IndexTime Factors

Identifiers

PMID21691341
PMCPMC6502251
OpenAlexW2095505246

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.