Evidence map›Paper›PMID 21689982›Full record

Trial reportSleep medicine2011

Echocardiographic findings in ischemic stroke patients with obstructive sleep apnea.

Anna Svatikova, Renuka Jain, Ronald D Chervin, Peter G Hagan, Devin L Brown

Open access · greenAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Sleep medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anna SvatikovaMayo School of Graduate Medical Education, Internal Medicine, Mayo Clinic, Siebens 5, 200 First Street SW, Rochester, MN 55905, USA.
Renuka Jain
Ronald D Chervin
Peter G Hagan
Devin L Brown
University of Michigan–Ann Arbor · USMayo Clinic · US

Funding

Treatment of Obstructive Sleep Apnea After StrokeK23NS051202 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROWN, DEVIN L · 2006 to 2010
$838k
NINDS NIH HHS K23 NS051202
6 · The paper itself

Abstract

backgroundObstructive sleep apnea (OSA) has been associated with cardiac abnormalities. Whether any cardiac dysfunction is present in ischemic stroke patients with OSA is not known. The purpose of this study was to compare echocardiographic findings in ischemic stroke patients with and without OSA.

methodsNocturnal polysomnography was performed on 28 ischemic stroke subjects within 7 days of symptom onset. OSA was defined as an apnea-hypopnea index of ≥10. Echocardiographic variables were compared between the OSA and non OSA groups using Wilcoxon signed-rank, chi-square, or Fisher's exact tests.

resultsThe 14 (50%) subjects with OSA had comparable cardiac function and structure to those without OSA (n=14). Left ventricular (LV) mass index, LV ejection fraction, LV diastolic function, left atrial area, and right ventricular systolic function were not different between groups. Ischemic stroke subjects, regardless of their OSA status, had LV diastolic dysfunction with preserved systolic function.

conclusionsSubjects with and without OSA, based on polysomnography in the first 7 days after stroke, have comparable right and left ventricular function.

Indexed as

EchocardiographyAcute DiseaseAgedAged, 80 and overBrain IschemiaContinuous Positive Airway PressureCross-Sectional StudiesFemaleHumansMaleMiddle AgedPilot ProjectsPolysomnographySleep Apnea, ObstructiveStrokeVentricular Dysfunction, Left

Identifiers

PMID21689982
PMCPMC3145249
OpenAlexW2019534686

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.