ArticleUltrasonics sonochemistry2012
Production of uniformly sized serum albumin and dextrose microbubbles.
Article in Ultrasonics sonochemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 51 citations in OpenAlex.
- Stimuli-Responsive Materials for Biomedical Applications.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Graphene-Loaded Aphron Microbubbles for Enhanced Drilling Fluid Performance and Carbon Capture and Storage.ACS applied nano materials · 2024Article
- Influence of protein nativity on the stability of bovine serum albumin coated microbubbles.iScience · 2024Article
- Late-Stage Functionalization of Living Organisms: Rethinking Selectivity in Biology.Chemical reviews · 2024Review
- Targeted Microbubbles for Drug, Gene, and Cell Delivery in Therapy and Immunotherapy.Pharmaceutics · 2023Review
- Microbubbles Stabilized by Protein Shell: From Pioneering Ultrasound Contrast Agents to Advanced Theranostic Systems.Pharmaceutics · 2022Review
- Air-Filled Bubbles Stabilized by Gold Nanoparticle/Photodynamic Dye Hybrid Structures for Theranostics.Nanomaterials (Basel, Switzerland) · 2021Article
- Characterising the cavitation activity generated by an ultrasonic horn at varying tip-vibration amplitudes.Ultrasonics sonochemistry · 2021Article
- Design of Albumin-Coated Microbubbles Loaded With Polylactide Nanoparticles.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2015Article
- A Novel Foam Contrast Agent Suitable for Fluoroscopic Interventional Procedure: Comparative Study of Physical Properties and Experimental Intervention in Animal Model.BioMed research international · 2015Article
- Synthesis and characterization of transiently stable albumin-coated microbubbles via a flow-focusing microfluidic device.Ultrasound in medicine & biology · 2014Article
- Effects of microbubble size on ultrasound-mediated gene transfection in auditory cells.BioMed research international · 2014Article
- Influence of microbubble size on postexcitation collapse thresholds for single ultrasound contrast agents using double passive cavitation detection.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2013Article
- Influences of microbubble diameter and ultrasonic parameters on in vitro sonothrombolysis efficacy.Journal of vascular and interventional radiology : JVIR · 2012Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Uniformly-sized preparations with average microbubble (MB) diameters from 1 to 7 μm were produced reliably by sonicating decafluorobutane-saturated solutions of serum albumin and dextrose. Detailed protocols for producing and size-separating the MBs are presented, along with the effects that changing each production parameter (serum albumin concentration, sonication power, sonication time, etc.) had on MB size distribution and acoustic stability. These protocols can be used to produce MBs for experimental applications or serve as templates for developing new protocols that yield MBs with physical and acoustic properties better suited to specific applications. Size stability and ultrasonic performance quality control tests were developed to assure that successive MB preparations perform identically and to distinguish the physical and acoustic properties of identically sized MBs produced with different serum albumin-dextrose formulations and sonication parameters. MBs can be stored at 5 °C for protracted periods (2 weeks to one year depending on formulation).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.