Evidence map›Paper›PMID 21689097›Full record

ArticleHealth services research2011

Does medication adherence following a copayment increase differ by disease burden?

Virginia Wang, Chuan-Fen Liu, Christopher L Bryson, Nancy D Sharp, Matthew L Maciejewski

Abstract read
In one paragraph

Article in Health services research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  7. The distributive fairness of out-of-pocket healthcare expenditure in the Russian Federation.International journal of health economics and management · 2020
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Virginia WangDivision of General Internal Medicine, Department of Medicine, Duke University, Durham, NC, USA. virginia.wang@duke.edu
Chuan-Fen Liu
Christopher L Bryson
Nancy D Sharp
Matthew L Maciejewski

Funding

Duke Mentored CER Scholar ProgramK12HS019479 · AHRQ · DUKE UNIVERSITY · PI ODDONE, EUGENE Z. · 2010 to 2010
$1.9M
AHRQ HHS K12 HS019479
6 · The paper itself

Abstract

objectivesTo compare changes in medication adherence between patients with high- or low-comorbidity burden after a copayment increase.

methodsWe conducted a retrospective observational study at four Veterans Affairs (VA) medical centers by comparing veterans with hypertension or diabetes required to pay copayments with propensity score-matched veterans exempt from copayments. Disease cohorts were stratified by Diagnostic Cost Group risk score: low- (<1) and high-comorbidity (>1) burden. Medication adherence from February 2001 to December 2003, constructed from VA pharmacy claims data based on the ReComp algorithm, were assessed using generalized estimating equations.

resultsVeterans with lower comorbidity were more responsive to a U.S.$5 copayment increase than higher comorbidity veterans. In the lower comorbidity groups, veterans with diabetes had a greater reduction in adherence than veterans with hypertension. Adherence trends were similar for copayment-exempt and nonexempt veterans with higher comorbidity.

conclusionMedication copayment increases are associated with different impacts for low- and high-risk patients. High-risk patients incur greater out-of-pocket costs from continued adherence, while low-risk patients put themselves at increased risk for adverse health events due to greater nonadherence.

Indexed as

Drug MonitoringAge FactorsAntidepressive AgentsAntihypertensive AgentsComorbidityDeductibles and CoinsuranceDepressionDiabetes MellitusHealth Services ResearchHumansHypertensionHypoglycemic AgentsRetrospective StudiesRisk FactorsSex FactorsSocioeconomic FactorsAntidepressive AgentsAntihypertensive AgentsHypoglycemic Agents

Identifiers

PMID21689097
PMCPMC3393028

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.