ReviewDevelopmental neurobiology2011
Extracellular matrix and its receptors in Drosophila neural development.
Review in Developmental neurobiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
52 citing papers in PubMed.
- Larval exposure to sertraline induces dose- and time-dependent remodeling of neuronal alternative splicing in adult Drosophila melanogaster.Molecular biology reports · 2026Article
- ALife science alliance · 2025Article
- The neuron-specific IIS/FOXO transcriptome in aged animals reveals regulatory mechanisms of cognitive aging.eLife · 2024Article
- Glia as Functional Barriers and Signaling Intermediaries.Cold Spring Harbor perspectives in biology · 2024Review
- Article
- Activation and expansion of presynaptic signaling foci drives presynaptic homeostatic plasticity.Neuron · 2022Article
- Integrin-ECM interactions and membrane-associated Catalase cooperate to promote resilience of the Drosophila intestinal epithelium.PLoS biology · 2022Article
- chinmo-mutant spermatogonial stem cells cause mitotic drive by evicting non-mutant neighbors from the niche.Developmental cell · 2022Article
- The exit of axons and glial membrane from the developing Drosophila retina requires integrins.Molecular brain · 2022Article
- Epithelial Cell Polarity DuringFrontiers in cell and developmental biology · 2022Review
- Role of juvenile hormone receptorZoological research · 2021Article
- Transcriptional Profiles of Diploid MutantInsects · 2021Article
- The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation.Nature communications · 2021Article
- Secreted C-type lectin regulation of neuromuscular junction synaptic vesicle dynamics modulates coordinated movement.Journal of cell science · 2021Article
- Review of Design Considerations for Brain-on-a-Chip Models.Micromachines · 2021Review
- Cyclic Strain and Electrical Co-stimulation Improve Neural Differentiation of Marrow-Derived Mesenchymal Stem Cells.Frontiers in cell and developmental biology · 2021Article
- Anti-Fibrotic Activity of an Antimicrobial Peptide in a Drosophila Model.Journal of innate immunity · 2021Article
- Mud Loss Restricts Yki-Dependent Hyperplasia inJournal of developmental biology · 2020Article
- Intramuscular Delivery of Gene Therapy for Targeting the Nervous System.Frontiers in molecular neuroscience · 2020Article
- How the extracellular matrix shapes neural development.Open biology · 2019Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Extracellular matrix (ECM) and matrix receptors are intimately involved in most biological processes. The ECM plays fundamental developmental and physiological roles in health and disease, including processes underlying the development, maintenance, and regeneration of the nervous system. To understand the principles of ECM-mediated functions in the nervous system, genetic model organisms like Drosophila provide simple, malleable, and powerful experimental platforms. This article provides an overview of ECM proteins and receptors in Drosophila. It then focuses on their roles during three progressive phases of neural development: (1) neural progenitor proliferation, (2) axonal growth and pathfinding, and (3) synapse formation and function. Each section highlights known ECM and ECM-receptor components and recent studies done in mutant conditions to reveal their in vivo functions, all illustrating the enormous opportunities provided when merging work on the nervous system with systematic research into ECM-related gene functions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.