ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2011
Main pulmonary artery diameter from attenuation correction CT scans in cardiac SPECT accurately predicts pulmonary hypertension.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- CT-base pulmonary artery measurement in the detection of pulmonary hypertension: a meta-analysis and systematic review.Medicine · 2014Pooled it
- Determining pulmonary artery diameter on CT scans as basis for performing transthoracic echocardiography to screen for pulmonary hypertension in patients with pulmonary artery enlargement.Journal of echocardiography · 2025Article
- Main pulmonary artery enlargement predicts 90-day readmissions in Chinese COPD patients.Journal of thoracic disease · 2021Article
- Pulmonary Vascular Manifestations of COVID-19 Pneumonia.Radiology. Cardiothoracic imaging · 2020Article
- Performance of pulmonary artery dimensions measured on high-resolution computed tomography scan for identifying pulmonary hypertension.ERJ open research · 2020Article
- Advanced imaging in pulmonary hypertension: emerging techniques and applications.The international journal of cardiovascular imaging · 2019Review
- Extracardiac findings on computed tomography attenuation correction: Is it worth paying extra attention?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Pulmonary Arterial Enlargement is Associated With Acute Chest Pain in Patients Without Obstructive Coronary Artery Disease.Clinical medicine insights. Circulatory, respiratory and pulmonary medicine · 2018Article
- Dyspnea predicts mortality among patients undergoing coronary computed tomographic angiography.The international journal of cardiovascular imaging · 2016Article
- Computed tomography measurement of pulmonary artery for diagnosis of COPD and its comorbidity pulmonary hypertension.International journal of chronic obstructive pulmonary disease · 2015Article
- Significance of main pulmonary artery dilation on imaging studies.Annals of the American Thoracic Society · 2014Review
- Pathophysiology and clinical implications of pulmonary arterial enlargement in COPD.International journal of chronic obstructive pulmonary disease · 2013Review
- Hypodense regions in unenhanced CT identify nonviable myocardium: validation versus 18F-FDG PET.European journal of nuclear medicine and molecular imaging · 2012Article
- In vivo and in vitro measurements of pulmonary arterial stiffness: A brief review.Pulmonary circulation · 2012Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo establish the value of the main pulmonary artery (MPA) diameter assessed from unenhanced computer tomography (CT) scans used for attenuation correction (AC) of single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) to predict pulmonary hypertension (PHT).
backgroundIn contrast-enhanced chest CT scans an MPA diameter of 29 mm or greater is an established predictor of PHT. However, it is unknown, whether measurements from an unenhanced CT scan for AC may be used as predictor of PHT.
methods100 patients underwent SPECT MPI for assessment of coronary artery disease. PHT was defined as a right ventriculo-atrial gradient of 30 mm Hg or greater by Doppler echocardiography. We compared MPA diameter from CT to SPECT findings (right ventricular hypertrophy/enlargement, septal wall motion abnormality/perfusion defect, and D-shape) to determine the best predictor of PHT.
resultsPHT was found in 37 patients. An MPA diameter of 30 mm or greater yielded a sensitivity, specificity, accuracy, positive, and negative predictive value of 78%, 91%, 86%, 83%, and 88%, respectively. This yielded an area under the ROC curve of 0.85.
conclusionsMPA diameter from low-dose unenhanced multi-slice CT reliably predicts PHT, providing an important added clinical value from AC for SPECT MPI.
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