ArticleFrontiers in microbiology2010
Defining pathogenic bacterial species in the genomic era.
Article in Frontiers in microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed.
- Development of surface enhanced Raman spectra coupled with machine learning analysis for differentiation of closely related species within Enterobacter cloacae complex.BMC microbiology · 2026Article
- Comparative genomic insights into the genus Pantoea: genetic determinants of ecological lifestyle diversity and plant growth-promoting potential.World journal of microbiology & biotechnology · 2026Article
- Metronidazole response profiles of Gardnerella species are congruent with phylogenetic and comparative genomic analyses.Genome medicine · 2025Article
- Ecogenomic insights into the resilience of keystone Blastococcus Species in extreme environments: a comprehensive analysis.BMC genomics · 2025Article
- Genome sequence-based species classification ofMicrobiology spectrum · 2024Article
- MAGs-centric crack: how long will, spore-positiveFrontiers in microbiology · 2024Article
- The ecological assembly of bacterial communities in Antarctic wetlands varies across levels of phylogenetic resolution.Environmental microbiology · 2022Article
- A Comparative Genomic Approach to Determine the Virulence Factors and Horizontal Gene Transfer Events of Clinical Acanthamoeba Isolates.Microbiology spectrum · 2022Article
- Article
- Pan-Genome Analysis Reveals Host-Specific Functional Divergences inMicroorganisms · 2021Article
- Comparative Genomic and Pan-Genomic Characterization ofFrontiers in microbiology · 2021Article
- Pseudomonas aeruginosa core metabolism exerts a widespread growth-independent control on virulence.Scientific reports · 2020Article
- Comparative and Evolutionary Genomics of Isolates Provide Insight into the Pathoadaptation of Aeromonas.Genome biology and evolution · 2020Article
- Insights Into Subspecies Discrimination Potentiality From Bacteria MALDI-TOF Mass Spectra by Using Data Mining and Diversity Studies.Frontiers in microbiology · 2020Article
- Determining the Genetic Characteristics of Resistance and Virulence of the "Epidermidis Cluster Group" Through Pan-Genome Analysis.Frontiers in cellular and infection microbiology · 2020Article
- The Pathobiome in Animal and Plant Diseases.Trends in ecology & evolution · 2019Review
- Revisiting the Evolution and Taxonomy of Clostridia, a Phylogenomic Update.Genome biology and evolution · 2019Article
- Local Diversification of Methicillin- ResistantFrontiers in microbiology · 2019Article
- Genomic Delineation of Zoonotic Origins ofFrontiers in public health · 2019Review
- MultiTwin: A Software Suite to Analyze Evolution at Multiple Levels of Organization Using Multipartite Graphs.Genome biology and evolution · 2018Article
Corrections and comments
- Retraction · 2026-07-20Author Unresponsive · Concerns/Issues about Referencing/Attributions · Duplication of/in Image · Investigation by Journal/Publisher · Investigation by Third Party · Objections by Author(s) ·
- Retracted
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Actual definitions of bacterial species are limited due to the current criteria of definition and the use of restrictive genetic tools. The 16S ribosomal RNA sequence, for example, has been widely used as a marker for phylogenetic analyses; however, its use often leads to misleading species definitions. According to the first genetic studies, removing a certain number of genes from pathogenic bacteria removes their capacity to infect hosts. However, more recent studies have demonstrated that the specialization of bacteria in eukaryotic cells is associated with massive gene loss, especially for allopatric endosymbionts that have been isolated for a long time in an intracellular niche. Indeed, sympatric free-living bacteria often have bigger genomes and exhibit greater resistance and plasticity and constitute species complexes rather than true species. Specialists, such as pathogenic bacteria, escape these bacterial complexes and colonize a niche, thereby gaining a species name. Their specialization allows them to become allopatric, and their gene losses eventually favor reductive genome evolution. A pathogenic species is characterized by a gene repertoire that is defined not only by genes that are present but also by those that are lacking. It is likely that current bacterial pathogens will disappear soon and be replaced by new ones that will emerge from bacterial complexes that are already in contact with humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.