ArticleFrontiers in microbiology2010
Circadian clock proteins in prokaryotes: hidden rhythms?
Article in Frontiers in microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 44 citations in OpenAlex.
- Cyanobacterial Circadian Clock: Molecular Mechanisms and Physiological Outputs.Plants (Basel, Switzerland) · 2026Review
- Article
- Photomorphogenesis of Myxococcus macrosporus: new insights for light-regulation of cell development.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024Article
- Two KaiABC systems control circadian oscillations in one cyanobacterium.Nature communications · 2024Article
- Diel Cycle Proteomics: Illuminating Molecular Dynamics in Purple Bacteria for Optimized Biotechnological Applications.International journal of molecular sciences · 2024Article
- New Awareness of the Interplay Between the Gut Microbiota and Circadian Rhythms.Polish journal of microbiology · 2023Article
- Studying the Human Microbiota: Advances in Understanding the Fundamentals, Origin, and Evolution of Biological Timekeeping.International journal of molecular sciences · 2023Review
- The Microbiome as a Circadian Coordinator of Metabolism.Endocrinology · 2020Review
- Microbes in the Era of Circadian Medicine.Frontiers in cellular and infection microbiology · 2020Review
- Article
- Molecular Interactions between Pathogens and the Circadian Clock.International journal of molecular sciences · 2019Review
- Holobiont chronobiology: mycorrhiza may be a key to linking aboveground and underground rhythms.Mycorrhiza · 2019Review
- Review
- Transcriptomic Changes inInternational journal of molecular sciences · 2019Article
- Single molecules can operate as primitive biological sensors, switches and oscillators.BMC systems biology · 2018Article
- Computing with biological switches and clocks.Natural computing · 2018Article
- Daily rhythmicity in coastal microbial mats.NPJ biofilms and microbiomes · 2018Article
- Minimal tool set for a prokaryotic circadian clock.BMC evolutionary biology · 2017Article
- Timing the day: what makes bacterial clocks tick?Nature reviews. Microbiology · 2017Review
- Evolution of KaiC-Dependent Timekeepers: A Proto-circadian Timing Mechanism Confers Adaptive Fitness in the Purple Bacterium Rhodopseudomonas palustris.PLoS genetics · 2016Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Circadian clock genes are vital features of eukaryotes that have evolved such that organisms can adapt to our planet's rotation in order to anticipate the coming day or night as well as unfavorable seasons. This circadian clock uses oscillation as a timekeeping element. However, circadian clock mechanisms exist also in prokaryotes. The circadian clock of Cyanobacteria is well studied. It is regulated by a cluster of three genes: kaiA, kaiB, and kaiC. In this review, we will discuss the circadian system in cyanobacteria, and provide an overview and updated phylogenetic analysis of prokaryotic organisms that contain the main circadian genes. It is evident that the evolution of the kai genes has been influenced by lateral transfers but further and deeper studies are needed to get an in depth understanding of the exact evolutionary history of these genes. Interestingly, Legionella pneumophila an environmental bacterium and opportunistic human pathogen that parasitizes protozoa in fresh water environments also contains kaiB and kaiC, but their functions are not known. All of the residues described for the biochemical functions of the main pacemaker KaiC in Synechococcus elongatus are also conserved in the L. pneumophila KaiC protein.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.