ArticlePloS one2011
Imperfect vaccine aggravates the long-standing dilemma of voluntary vaccination.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Behavioural change models for infectious disease transmission: a systematic review (2010-2015).Journal of the Royal Society, Interface · 2016Pooled it
- Modelling assessment of epidemiological strategies based on self-screening tools.Communications medicine · 2026Article
- A behavioral game-theoretic model for vaccination with fractional-order imitation and aspiration dynamics.Scientific reports · 2025Article
- Social imitation dynamics of vaccination driven by vaccine effectiveness and beliefs.PLoS computational biology · 2025Article
- Exploring epidemic voluntary vaccinating behavior based on information-driven decisions and benefit-cost analysis.Applied mathematics and computation · 2023Article
- Exploring the performance of volatile mutations on evolutionary game dynamics in complex networks.Heliyon · 2023Article
- Impact of human cooperation on vaccination behaviors.Heliyon · 2023Article
- Impact of voluntary testing on infectious disease epidemiology: A game theoretic approach.PloS one · 2023Article
- Article
- A game-theoretic model of rabies in domestic dogs with multiple voluntary preventive measures.Journal of mathematical biology · 2022Article
- How growers make decisions impacts plant disease control.PLoS computational biology · 2022Article
- Vaccination games in prevention of infectious diseases with application to COVID-19.Chaos, solitons, and fractals · 2022Article
- Optimal governance and implementation of vaccination programmes to contain the COVID-19 pandemic.Royal Society open science · 2021Article
- Pair approximation model for the vaccination game: predicting the dynamic process of epidemic spread and individual actions against contagion.Proceedings. Mathematical, physical, and engineering sciences · 2021Article
- Decisions and disease: a mechanism for the evolution of cooperation.Scientific reports · 2020Article
- A novel route to cyclic dominance in voluntary social dilemmas.Journal of the Royal Society, Interface · 2020Article
- Article
- The impact of rare but severe vaccine adverse events on behaviour-disease dynamics: a network model.Scientific reports · 2019Article
- Imperfect vaccine and hysteresis.Proceedings. Biological sciences · 2019Article
- Interplay between cost and benefits triggers nontrivial vaccination uptake.Physical review. E · 2018Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Achieving widespread population immunity by voluntary vaccination poses a major challenge for public health administration and practice. The situation is complicated even more by imperfect vaccines. How the vaccine efficacy affects individuals' vaccination behavior has yet to be fully answered. To address this issue, we combine a simple yet effective game theoretic model of vaccination behavior with an epidemiological process. Our analysis shows that, in a population of self-interested individuals, there exists an overshooting of vaccine uptake levels as the effectiveness of vaccination increases. Moreover, when the basic reproductive number, R0, exceeds a certain threshold, all individuals opt for vaccination for an intermediate region of vaccine efficacy. We further show that increasing effectiveness of vaccination always increases the number of effectively vaccinated individuals and therefore attenuates the epidemic strain. The results suggest that 'number is traded for efficiency': although increases in vaccination effectiveness lead to uptake drops due to free-riding effects, the impact of the epidemic can be better mitigated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.