Evidence map›Paper›PMID 21687546›Full record

ArticleJournal of biomedicine & biotechnology2011

Histamine blood concentration in ischemic heart disease patients.

Vladimir Zdravkovic, Suzana Pantovic, Gvozden Rosic, Aleksandra Tomic-Lucic, Nemanja Zdravkovic, Maja Colic, Zdravko Obradovic, Mirko Rosic

Abstract read
In one paragraph

Article in Journal of biomedicine & biotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Function and Role of Histamine HPharmaceuticals (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Article
  9. The Roles of Cardiovascular HFrontiers in pharmacology · 2021
    Review
  10. Histamine and histidine decarboxylase: Immunomodulatory functions and regulatory mechanisms.Genes to cells : devoted to molecular & cellular mechanisms · 2020
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Stress triggers coronary mast cells leading to cardiac events.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2014
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vladimir ZdravkovicDepartment of Physiology, Faculty of Medicine, University of Kragujevac, Kragujevac, Serbia.
Suzana Pantovic
Gvozden Rosic
Aleksandra Tomic-Lucic
Nemanja Zdravkovic
Maja Colic
Zdravko Obradovic
Mirko Rosic

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate histamine blood concentration in subjects suffering from different types of ischemic heart diseases during the period of eight days. Our results showed that the histamine blood level was associated with different types of ischemic heart diseases. The blood histamine level in all investigated patients was significantly higher when compared to control subjects (44.87 ± 1.09 ng mL(-1)), indicating the increase of histamine release in patients suffering from coronary diseases. In patients suffering from ACS-UA and ACS-STEMI, the second day peak of histamine level occurs (90.85 ± 6.34 ng mL(-1) and 121.7 ± 6.34 ng mL(-1), resp.) probably as the reperfusion event. Furthermore, our data suggest that histamine can be additional parameter of myocardial ischemia along with cardiac specific enzymes and may prove to be an excellent single prognostic marker for multitude of ischemic heart diseases.

Indexed as

Acute Coronary SyndromeAdultAgedCoronary Artery DiseaseCoronary OcclusionFemaleHistamineHumansMaleMiddle AgedMyocardial IschemiaTroponin IHistamineTroponin I

Identifiers

PMID21687546
PMCPMC3114553

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.