Evidence map›Paper›PMID 21687432›Full record

ArticleFrontiers in microbiology2011

Salmonella - at home in the host cell.

Preeti Malik-Kale, Carrie E Jolly, Stephanie Lathrop, Seth Winfree, Courtney Luterbach, Olivia Steele-Mortimer

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Protein-centric mechanisms of typhoidalFrontiers in cellular and infection microbiology · 2026
    Review
  2. Article
  3. Infection biology ofEcoSal Plus · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. FromACS omega · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Mechanisms for the Invasion and Dissemination ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
    Review
  13. The Game for Three:Frontiers in microbiology · 2022
    Review
  14. Review
  15. Article
  16. Article
  17. Proteomic Analysis ofMolecular & cellular proteomics : MCP · 2020
    Article
  18. Article
  19. Article
  20. The Virulence Polysaccharide ofFrontiers in cellular and infection microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Preeti Malik-KaleLaboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institutes of Allergy and Infectious Disease, National Institute of Health Hamilton, MT, USA.
Carrie E Jolly
Stephanie Lathrop
Seth Winfree
Courtney Luterbach
Olivia Steele-Mortimer

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Gram-negative bacterium Salmonella enterica has developed an array of sophisticated tools to manipulate the host cell and establish an intracellular niche, for successful propagation as a facultative intracellular pathogen. While Salmonella exerts diverse effects on its host cell, only the cell biology of the classic "trigger"-mediated invasion process and the subsequent development of the Salmonella-containing vacuole have been investigated extensively. These processes are dependent on cohorts of effector proteins translocated into host cells by two type III secretion systems (T3SS), although T3SS-independent mechanisms of entry may be important for invasion of certain host cell types. Recent studies into the intracellular lifestyle of Salmonella have provided new insights into the mechanisms used by this pathogen to modulate its intracellular environment. Here we discuss current knowledge of Salmonella-host interactions including invasion and establishment of an intracellular niche within the host.

Indexed as

effectorsinvasionmembrane tubulesphagosometype III secretion systemvacuole

Identifiers

PMID21687432
PMCPMC3109617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.