Evidence map›Paper›PMID 21687401›Full record

ArticleFrontiers in microbiology2011

Mycobacterium Tuberculosis Infection and Inflammation: what is Beneficial for the Host and for the Bacterium?

Smitha J Sasindran, Jordi B Torrelles

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Observational
  8. Review
  9. Protein-Mediated Virulence in Mycobacterium tuberculosis.Advances in experimental medicine and biology · 2026
    Review
  10. Article
  11. Article
  12. Journal of pharmacopuncture · 2025
    Article
  13. Article
  14. Review
  15. Vaccines · 2025
    Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article

68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Smitha J SasindranCenter for Microbial Interface Biology, Division of Infectious Diseases, Department of Internal Medicine, The Ohio State University Columbus, OH, USA.
Jordi B Torrelles

Funding

Remodeling of the M. tuberculosis cell wall by the host microenvironmentR00AI073856 · NIAID · OHIO STATE UNIVERSITY · PI TORRELLES, JORDI B · 2009 to 2010
$561k
Remodeling of the M. tuberculosis cell wall by the host microenvironmentK99AI073856 · NIAID · OHIO STATE UNIVERSITY · PI TORRELLES, JORDI B · 2008 to 2008
$90k
NIAID NIH HHS K99 AI073856NIAID NIH HHS R00 AI073856
6 · The paper itself

Abstract

Tuberculosis is still a major health problem in the world. Initial interactions between Mycobacterium tuberculosis and the host mark the pathway of infection and the subsequent host inflammatory response. This inflammatory response is tightly regulated by both the host and the bacterium during different stages of infection. As infection progresses, the initial intense pro-inflammatory response observed is regulated by suppressive mediators balancing inflammation. In this environment, M. tuberculosis battles to survive interfering with the host inflammatory response. In this review we discuss the major effector molecules involved in inflammation in relation to the different stages of M. tuberculosis infection.

Indexed as

inflammationMycobacterium tuberculosispattern recognition receptorstuberculosis

Identifiers

PMID21687401
PMCPMC3109289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.