ArticleGefahrstoffe, Reinhaltung der Luft = Air quality control2011
Polychlorinated Biphenyl (PCB) carcinogenicity with special emphasis on airborne PCBs.
Article in Gefahrstoffe, Reinhaltung der Luft = Air quality control, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 68 citations in OpenAlex.
- Polychlorinated Biphenyls, Oxidative Stress, and Brain Health: Mechanistic Links to Neurodegenerative and Neurodevelopmental Diseases.Antioxidants (Basel, Switzerland) · 2026Review
- A Scoping Review of Neurotoxic and Behavioral Outcomes Following Polychlorinated Biphenyl (PCB) Exposure in Post-Weaned Rodents.International journal of molecular sciences · 2025Article
- Epidermal growth factor receptor in placental health and disease: pathways, dysfunction, and chemical disruption.Toxicological sciences : an official journal of the Society of Toxicology · 2025Review
- Complex roles for sulfation in the toxicities of polychlorinated biphenyls.Critical reviews in toxicology · 2024Review
- Cancer Risk following Residential Exposure to Airborne Polychlorinated Biphenyls: A Danish Register-Based Cohort Study.Environmental health perspectives · 2022Article
- Review
- Hydroxylated Polychlorinated Biphenyls Are Emerging Legacy Pollutants in Contaminated Sediments.Environmental science & technology · 2022Article
- A state-of-the-science review of polychlorinated biphenyl exposures at background levels: relative contributions of exposure routes.The Science of the total environment · 2021Article
- Effect of prevalent polychlorinated biphenyls (PCBs) food contaminant on the MCF7, LNCap and MDA-MB-231 cell lines viability and PON1 gene expression level: proposed model of binding.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2021Article
- Detection and Quantification of Polychlorinated Biphenyl Sulfates in Human Serum.Environmental science & technology · 2021Article
- 3,3'-Dichlorobiphenyl Is Metabolized to a Complex Mixture of Oxidative Metabolites, Including Novel Methoxylated Metabolites, by HepG2 Cells.Environmental science & technology · 2020Article
- Endocrine disruptors from the environment affecting breast cancer.Oncology letters · 2020Review
- Review on the Structures and Activities of Transthyretin Amyloidogenesis Inhibitors.Drug design, development and therapy · 2020Review
- The spatial distribution of congener-specific human PCB concentrations in a PCB-polluted region.The Science of the total environment · 2019Article
- Persistent organic pollutants as predictors of increased FSH:LH ratio in naturally cycling, reproductive age women.Environmental research · 2018Article
- Sources and toxicities of phenolic polychlorinated biphenyls (OH-PCBs).Environmental science and pollution research international · 2018Article
- Stable genetic structure and connectivity in pollution-adapted and nearby pollution-sensitive populations ofRoyal Society open science · 2018Article
- Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1.Environmental toxicology and pharmacology · 2018Article
- Identification of lipidomic markers of chronic 3,3',4,4',5-pentachlorobiphenyl (PCB 126) exposure in the male rat liver.Toxicology · 2017Article
- Identification of a sulfate metabolite of PCB 11 in human serum.Environment international · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Polychlorinated biphenyls (PCBs) are industrial chemicals used in various applications requiring chemical stabilityand have now become widely dispersed. Their characteristics of persistence, low water/higher lipid solubility, contribute to their ability to bioconcentrate and bioaccumulate. Traditionally PCBs have been regulated as food contaminants and the general population is primarily exposed by that route. PCBs in foodstuffs are generally higher chlorinated, resistant to metabolic breakdown, and elicit toxic changes that are thought to be predominantly receptor/parent PCB-driven. But for certain occupational exposures, and for those persons residing or working in contaminated buildings, and in large cities, an inhalation route of exposure may predominate. Airborne PCBs are, in contrast to foodborne PCBs, lower chlorinated, more volatile, and subject to metabolic attack. In this review, we have explored (geno-) toxic manifestations of PCBs typical of those found in air. Here metabolic conversion of the parent PCB to hydroxylated and other metabolic progeny appear to play a dominant role, especially in genotoxicity. We should be cognizant of the impact of exposures to airborne PCBs for those individuals who are occupationally exposed, for persons living near contaminated sites, for those who work or go to school in contaminated buildings, and especially cognizant of the young, the socio-economically disadvantaged and medically-underserved or nutritionally-deficient populations.
Identifiers
21686028PMC3113507W2244019953What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.