DNMT3A mutations are rare in childhood acute myeloid leukemia.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed, 37 citations in OpenAlex.

1. DNA methyltransferase 3a hot-spot locus is not mutated in pediatric patients affected by acute myeloid or T-cell acute lymphoblastic leukemia: an Italian study.Haematologica · 2011
   Trial
2. The impact of DNMT3A variant allele frequency and two different comutations on patients with de novo cytogenetically normal acute myeloid leukemia.Cancer medicine · 2023
   Article
3. Epigenetic regulation in hematopoiesis and its implications in the targeted therapy of hematologic malignancies.Signal transduction and targeted therapy · 2023
   Review
4. Proviral Integration of Moloney Virus-2 (PIM-2) Expression Level as a Prognostic Marker in Patients with Acute Myeloid Leukemia.International journal of general medicine · 2022
   Article
5. Archives of medical science : AMS · 2017
   Article
6. DNMT3A mutations in Chinese childhood acute myeloid leukemia.Medicine · 2017
   Article
7. DNMT3A in Leukemia.Cold Spring Harbor perspectives in medicine · 2017
   Review
8. Gene Mutations as Emerging Biomarkers and Therapeutic Targets for Relapsed Acute Myeloid Leukemia.Frontiers in pharmacology · 2017
   Review
9. DNMT3A in haematological malignancies.Nature reviews. Cancer · 2015
   Review
10. SWI/SNF Subunits SMARCA4, SMARCD2 and DPF2 Collaborate in MLL-Rearranged Leukaemia Maintenance.PloS one · 2015
    Article
11. Genomic characterization of acute leukemias.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2014
    Review
12. Molecular therapeutic approaches for pediatric acute myeloid leukemia.Frontiers in oncology · 2014
    Review
13. Mutations in DNA methyltransferase (DNMT3A) observed in acute myeloid leukemia patients disrupt processive methylation.The Journal of biological chemistry · 2012
    Article
14. A somatic EZH2 mutation in childhood acute myeloid leukemia.Leukemia · 2012
    Article
15. Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association.Leukemia · 2012
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

6 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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