Evidence map›Paper›PMID 21684382›Full record

ReviewLancet (London, England)2011

Osteoarthritis: an update with relevance for clinical practice.

Johannes W J Bijlsma, Francis Berenbaum, Floris P J G Lafeber

4 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Lancet (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 979 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
979citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03141853 nacompletednot on this mapstarted 2017, after this paper: background citation

Equine-assisted Therapy for Adults and Older Adults With Arthritis: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of Missouri, Kansas CityRan2017 to 2017Enrolled21ConditionsArthritisArmsEquine-assisted Therapy, Arthritis Exercise Education
NCT03601533 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Prospective Study of the Efficacy of Ultrasound-guided Genicular Nerve Block With Phenol for the Treatment of Chronic Pain Due to Knee Osteoarthritis

TypeinterventionalSponsorFederal University of São PauloRan2018 to 2018Enrolled15ConditionsOsteoarthritis, Knee, Chronic PainArmsPhenol
NCT04061733 naunknown statusnot on this mapstarted 2019, after this paper: background citation

New Hydroxyethyl Cellulose Hydrogel for the Treatment of the Pain of Knee Arthrosis

TypeinterventionalSponsorPromedonRan2019 to 2024Enrolled50ConditionsOsteoarthritis, Knee, PainArmsHydrogel injection
NCT04106986 nacompletednot on this mapstarted 2019, after this paper: background citation

The Effect Of Pulsed Electromagnetic Field And Progressive Resistance Exercise On Knee Osteoarthritis

TypeinterventionalSponsorJordan University of Science and TechnologyRan2019 to 2020Enrolled32ConditionsKnee OsteoarthritisArmsPulsed electromagnetic field and Progressives resistance exercise, PRE
3 · Its place in the literature

Who cites it

979 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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919 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Johannes W J BijlsmaDepartment of Rheumatology and Clinical Immunology, University Medical Centre Utrecht, Utrecht, Netherlands. j.w.j.bijlsma@umcutrecht.nl
Francis Berenbaum
Floris P J G Lafeber

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis is thought to be the most prevalent chronic joint disease. The incidence of osteoarthritis is rising because of the ageing population and the epidemic of obesity. Pain and loss of function are the main clinical features that lead to treatment, including non-pharmacological, pharmacological, and surgical approaches. Clinicians recognise that the diagnosis of osteoarthritis is established late in the disease process, maybe too late to expect much help from disease-modifying drugs. Despite efforts over the past decades to develop markers of disease, still-imaging procedures and biochemical marker analyses need to be improved and possibly extended with more specific and sensitive methods to reliably describe disease processes, to diagnose the disease at an early stage, to classify patients according to their prognosis, and to follow the course of disease and treatment effectiveness. In the coming years, a better definition of osteoarthritis is expected by delineating different phenotypes of the disease. Treatment targeted more specifically at these phenotypes might lead to improved outcomes.

Indexed as

OsteoarthritisAnti-Inflammatory Agents, Non-SteroidalHand JointsHumansOsteoarthritis, HipOsteoarthritis, KneeAnti-Inflammatory Agents, Non-Steroidal

Identifiers

PMID21684382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.