Evidence map›Paper›PMID 21684218›Full record

ArticleThe journal of pain2011

Occurrence and characteristics of chronic pain in a community-based cohort of indigent adults living with HIV infection.

Christine Miaskowski, Joanne M Penko, David Guzman, Jennifer E Mattson, David R Bangsberg, Margot B Kushel

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in The journal of pain, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05554146 (The Impact of Medical Cannabis on Pain and Inflammation in People Living With HIV), which is not on this map. Cited by 123 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
123citing papers in PubMed, 5 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05554146 nacompletednot on this mapstarted 2022, after this paper: background citation

The Impact of Medical Cannabis on Pain and Inflammation in People Living With HIV

TypeinterventionalSponsorMontefiore Medical CenterRan2022 to 2024Enrolled35ConditionsHIV Infections, Neuropathic Pain, CannabisArmsReceipt of Coupon for Placebo Soft-Gel Capsule, Receipt of Coupon for High THC Soft-Gel Capsule, Receipt of Coupon for Equal THC and CBD Soft-Gel Capsule, Receipt of Coupon for High CBD Soft-Gel Capsule
3 · Its place in the literature

Who cites it

123 citing papers in PubMed, 5 syntheses or guidelines pooled it, 179 citations in OpenAlex.

  1. Pooled it
  2. 2017 HIVMA of IDSA Clinical Practice Guideline for the Management of Chronic Pain in Patients Living With HIV.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Guideline
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  5. Pain in people living with HIV/AIDS: a systematic review.Journal of the International AIDS Society · 2014
    Pooled it
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63 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Christine MiaskowskiDepartment of Physiological Nursing, University of California, San Francisco, California, USA.
Joanne M Penko
David Guzman
Jennifer E Mattson
David R Bangsberg
Margot B Kushel
San Francisco General Hospital · USHarvard University · USUniversity of California, San Francisco · US

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
TB PREVENTION AND HIV IN THE HOMELESS--AN INTERVENTIONR01MH054907 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BANGSBERG, DAVID ROY · 1995 to 2014
$20.7M
Aging Among the Homeless: Social Isolation, Function and Institutional CareR01AG041860 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Margot B Kushel · 2012 to 2026
$9.3M
Pain and Misuse of Prescription Opioids in a Community-Based HIV-Infected CohortR01DA022550 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KUSHEL, MARGOT B · 2006 to 2009
$1.4M
Mentoring Patient Oriented Adherence Research in UgandaK24MH087227 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI BANGSBERG, DAVID ROY · 2009 to 2013
$776k
NCRR NIH HHS UL1 RR024131NCRR NIH HHS UL1RR024131NIA NIH HHS R01 AG041860NIDA NIH HHS R01 DA022550NIMH NIH HHS K24 MH087227NIMH NIH HHS R01 MH054907
6 · The paper itself

Abstract

unlabelledPain is common among people living with HIV/AIDS (PLWHA), but little is known about chronic pain in socioeconomically disadvantaged HIV-infected populations with high rates of substance abuse in the postantiretroviral era. This cross-sectional study describes the occurrence and characteristics of pain in a community-based cohort of 296 indigent PLWHA. Participants completed questionnaires about sociodemographics, substance use, depression, and pain. Cut-point analysis was used to generate categories of pain severity. Of the 270 participants who reported pain or the use of a pain medication in the past week, 8.2% had mild pain, 38.1% had moderate pain, and 53.7% had severe pain. Female sex and less education were associated with more severe pain. Depression was more common among participants with severe pain than among those with mild pain. Increasing pain severity was associated with daily pain and with chronic pain. Over half of the participants reported having a prescription for an opioid analgesic. Findings from this study suggest that chronic pain is a significant problem in this high risk, socioeconomically disadvantaged group of patients with HIV disease and high rates of previous or concurrent use of illicit drugs. PERSPECTIVE: This article presents epidemiological data showing that unrelieved chronic pain is a significant problem for indigent people living with HIV. Participants reported pain severity similar to those with metastatic cancer. Despite high rates of substance use disorders, approximately half received prescriptions for opioid analgesics, although few for long-acting agents.

Indexed as

PovertyResidence CharacteristicsAdultAnalgesics, OpioidChronic PainCohort StudiesFemaleHIV InfectionsHumansLongitudinal StudiesMaleMiddle AgedPain MeasurementSubstance-Related DisordersAnalgesics, Opioid

Identifiers

PMID21684218
PMCPMC3164738
OpenAlexW1988827086

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.