Evidence map›Paper›PMID 21683049›Full record

ArticleJournal of studies on alcohol and drugs2011

A longitudinal examination of alcohol pharmacotherapy adoption in substance use disorder treatment programs: patterns of sustainability and discontinuation.

Amanda J Abraham, Hannah K Knudsen, Paul M Roman

Open access · bronzeAbstract read
In one paragraph

Article in Journal of studies on alcohol and drugs, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Article
  3. Availability of Medications for the Treatment of Alcohol and Opioid Use Disorder in the USA.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Amanda J AbrahamInstitute for Behavioral Research, University of Georgia, Athens, 30602-2401, USA. aabraham@uga.edu
Hannah K Knudsen
Paul M Roman
University of Georgia · US

Funding

CTN Membership and Adoption of Innovative Tx PracticesR01DA014482 · NIDA · UNIVERSITY OF GEORGIA (UGA) · PI ROMAN, PAUL M · 2001 to 2011
$8.0M
ADOPTION OF INNOVATIONS IN PRIVATE A&D TREATMENT CENTERSR01DA013110 · NIDA · UNIVERSITY OF GEORGIA (UGA) · PI ROMAN, PAUL M · 1999 to 2010
$4.9M
Use of Evidence-based Practices in Alcoholism TreatmentR01AA015974 · NIAAA · UNIVERSITY OF GEORGIA · PI ROMAN, PAUL M · 2008 to 2012
$3.0M
Diffusion, Adoption, and Implementation of Pharmacotherapies in Alcohol TxF32AA016872 · NIAAA · UNIVERSITY OF GEORGIA · PI ABRAHAM, AMANDA J · 2007 to 2009
$144k
NIAAA NIH HHS F32 AA016872NIAAA NIH HHS F32AA016872NIAAA NIH HHS R01 AA015974NIAAA NIH HHS R01AA015974NIDA NIH HHS R01 DA013110NIDA NIH HHS R01DA013110NIDA NIH HHS R01 DA014482NIDA NIH HHS R01DA14482
6 · The paper itself

Abstract

objectiveThe objectives of this study were to (a) identify the patterns of disulfiram (Antabuse) and tablet naltrexone (Revia) adoption over a 48-month period in a nationally representative sample of privately funded programs that deliver substance use disorder treatment; (b) examine predictors of sustainability, later adoption, discontinuation, and nonadoption of disulfiram and tablet naltrexone; and (c) measure reasons for medication discontinuation.

methodTwo waves of data were collected via face-to-face structured interviews with 223 program administrators.

resultsThese data demonstrated that adoption of medications for alcohol use disorders (AUDs) was a dynamic process. Although nonadoption was the most common pattern, approximately 20% of programs sustained use of the AUD medications and 30% experienced organizational change in adoption over the study period. Bivariate multinomial logistic regression models revealed that organizational characteristics were associated with sustainability including location in a hospital setting, program size, accreditation, revenues from private insurance, referrals from the criminal justice system, number of medical staff, and use of selective serotonin reuptake inhibitors at baseline. Two patterns of discontinuation were found: Programs either discontinued use of all substance use disorder medications or replaced disulfiram/tablet naltrexone with a newer AUD medication.

conclusionsThese findings suggest that adoption of AUD medications may be positively affected by pressure from accreditation bodies, partnering with primary care physicians, medication-specific training for medical staff, greater availability of resources to cover the costs associated with prescribing AUD medications, and amending criminal justice contracts to include support for AUD medication use.

Indexed as

Alcohol DeterrentsAlcoholismAlcohol-Related DisordersDatabases, FactualDisulfiramDrug UtilizationEthanolHumansLongitudinal StudiesNaltrexonePractice Patterns, Physicians'Substance Abuse Treatment CentersTime FactorsAlcohol DeterrentsDisulfiramEthanolNaltrexone

Identifiers

PMID21683049
PMCPMC3125890
OpenAlexW2132521887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.