Evidence map›Paper›PMID 21682750›Full record

ReviewImmunological reviews2011

Anaphylaxis: a history with emphasis on food allergy.

Stephen R Boden, A Wesley Burks

Open access · greenAbstract readReview
In one paragraph

Review in Immunological reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Article
  3. A case of anaphylaxis after ingestion ofAsia Pacific allergy · 2020
    Article
  4. Microbial interactions in the atopic march.Clinical and experimental immunology · 2020
    Review
  5. Review
  6. Article
  7. Article
  8. Food-Induced Acute Pancreatitis.Digestive diseases and sciences · 2017
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Food allergy and quality of life: what have we learned?Current allergy and asthma reports · 2013
    Review
  15. Article
  16. Basophils and allergic inflammation.The Journal of allergy and clinical immunology · 2013
    Review
  17. Lymphatic diamine oxidase secretion stimulated by fat absorption is linked with histamine release.American journal of physiology. Gastrointestinal and liver physiology · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stephen R BodenDivision of Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA.
A Wesley Burks
Duke University · US

Funding

RESEARCH TRAINING IN ALLERGY AND CLINICAL IMMUNOLOGYT32AI007062 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David B. Peden, John W. Sleasman · 1985 to 2026
$6.1M
Understanding the Mechanism of Mucosal ImmunotherapyR01AI068074 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BURKS, A. WESLEY · 2007 to 2016
$3.8M
NIAID NIH HHS R01 AI068074NIAID NIH HHS T32 AI007062
6 · The paper itself

Abstract

In the century since Paul Portier and Charles Richet described their landmark findings of severe fatal reactions in dogs re-exposed to venom after vaccination with sea anemone venom, treatment for anaphylaxis continues to evolve. The incidence of anaphylaxis continues to be difficult to measure. Underreporting due to patients not seeking medical care as well as failure to identify anaphylaxis affects our understanding of the magnitude of the disease. Treatment with intramuscular epinephrine continues to be the recommended first-line therapy, although studies indicate that education of both the patients and the medical community is needed. Adverse food reactions continue to be the leading cause of anaphylaxis presenting for emergency care. Current therapy for food-induced anaphylaxis is built on the foundation of strict dietary avoidance, rapid access to injectable epinephrine, and education to recognize signs and symptoms of anaphylaxis. Investigation into therapy with oral and sublingual immunotherapy as well as other modalities holds hope for improved treatment of food-induced anaphylaxis.

Indexed as

AllergensAnaphylaxisAnimalsBasophilsCnidarian VenomsCytokinesDietDogsEpinephrineFood HypersensitivityHistamineHumansImmunoglobulin EImmunotherapyInjections, IntramuscularMast CellsAllergensCnidarian VenomsCytokinesEpinephrineHistamineImmunoglobulin EProstaglandinsSympathomimetics

Identifiers

PMID21682750
PMCPMC3122150
OpenAlexW1869004279

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.